Birkebaek N H, Perrild B D
Department of Paediatrics, Herning Hospital, Denmark.
Pediatr Hematol Oncol. 1986;3(3):283-5. doi: 10.3109/08880018609031228.
A pheochromocytoma was diagnosed in a 14-year-old boy developing hypertension after treatment with imipramine for primary nocturnal enuresis. The mechanism of action is assumed to be an inhibition of the neuronal uptake of catecholamines being released in large quantities from the tumor. The diagnosis of pheochromocytoma should be considered in patients developing hypertension during treatment with cyclic antidepressants.
一名14岁男孩在用丙咪嗪治疗原发性夜间遗尿症后出现高血压，被诊断为嗜铬细胞瘤。其作用机制被认为是抑制了从肿瘤大量释放的儿茶酚胺的神经元摄取。在用环类抗抑郁药治疗期间出现高血压的患者应考虑嗜铬细胞瘤的诊断。
