Imai Naohiko, Sumi Hirofumi, Shibagaki Yugo
Division of Nephrology and Hypertension, Department of Internal Medicine, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, Japan.
Int J Emerg Med. 2019 Sep 18;12(1):29. doi: 10.1186/s12245-019-0246-7.
Hypernatremia is one of the most commonly encountered electrolyte disorders in the emergency department (ED). Few studies have reported the seasonal fluctuations of the prevalence of hypernatremia with conflicting results. We investigated the seasonal prevalence of hypernatremia in an emergency department in Japan.
A total of 12,598 patients presented to the ED between January 2015 and December 2017 were reviewed. The adult group aged between 18 and 64 years old consisted of 5427 patients and the elderly group aged over 65 years consisted of 7171 patients. Information collected included age, sex, serum sodium, and serum creatinine. Hypernatremia was defined as a serum sodium leve1 > 145 mEq/L, and moderate to severe hypernatremia was defined as a serum sodium level ≥ 150 mEq/L.
The prevalence of hypernatremia was significantly higher in the elderly group than in the adult group (2.6% vs. 0.7%; p < 0.001). Similarly, the prevalence of moderate to severe hypernatremia was significantly higher in the elderly group than in the adult group (1.0% vs. 0.1%; p < 0.001). The prevalence of hypernatremia and moderate to severe hypernatremia was significantly higher in the elderly group than in the adult group in all seasons. In the elderly group, the seasonal prevalence of moderate to severe hypernatremia was significantly higher during the winter. Also, there was a correlation between weather temperature and the prevalence of moderate to severe hypernatremia in the elderly group (r = - 0.34, p = 0.04).
Hypernatremia is prevalent in the elderly and the prevalence is highest during the winter. Special attention should be paid in the elderly patients to prevent hypernatremia especially in the winter.
高钠血症是急诊科最常见的电解质紊乱之一。很少有研究报道过高钠血症患病率的季节性波动,结果相互矛盾。我们调查了日本一家急诊科高钠血症的季节性患病率。
回顾了2015年1月至2017年12月期间共12598例到急诊科就诊的患者。年龄在18至64岁之间的成年组有5427例患者,65岁以上的老年组有7171例患者。收集的信息包括年龄、性别、血清钠和血清肌酐。高钠血症定义为血清钠水平>145 mEq/L,中度至重度高钠血症定义为血清钠水平≥150 mEq/L。
老年组高钠血症的患病率显著高于成年组(2.6%对0.7%;p<0.001)。同样,老年组中度至重度高钠血症的患病率也显著高于成年组(1.0%对0.1%;p<0.001)。在所有季节中,老年组高钠血症和中度至重度高钠血症的患病率均显著高于成年组。在老年组中,冬季中度至重度高钠血症的季节性患病率显著更高。此外,老年组中度至重度高钠血症的患病率与天气温度之间存在相关性(r=-0.34,p=0.04)。
高钠血症在老年人中普遍存在,且在冬季患病率最高。应特别关注老年患者,尤其是在冬季预防高钠血症。