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新月体性IgA肾病合并肾移植中同时出现的细胞介导和抗体介导的排斥反应，导致移植肾迅速失功。

Crescentic IgA nephropathy along with simultaneous cellular and antibody-mediated rejection in a kidney transplant leading to rapid allograft failure.

作者信息

Gani Imran, Kleven Daniel, Mulloy Laura

机构信息

Department of Nephrology, Hypertension and Transplant Medicine Augusta University Health Augusta GA USA.

Department of Pathology Augusta University Health Augusta GA USA.

出版信息

Clin Case Rep. 2019 Aug 12;7(9):1773-1776. doi: 10.1002/ccr3.2364. eCollection 2019 Sep.

DOI:10.1002/ccr3.2364
PMID:31534747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6745376/
Abstract

Crescentic IgA Nephropathy in a renal transplant can lead to rapid loss of graft function despite treatment. Concurrent treatment-resistant acute cellular and antibody-mediated rejection make the prognosis even worse.

摘要

肾移植中的新月体性IgA肾病即使经过治疗也可能导致移植肾功能迅速丧失。同时存在治疗抵抗性急性细胞性排斥反应和抗体介导的排斥反应会使预后更差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/0551d4e95f53/CCR3-7-1773-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/3dfc32861acd/CCR3-7-1773-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/5f6f223cdb10/CCR3-7-1773-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/0551d4e95f53/CCR3-7-1773-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/3dfc32861acd/CCR3-7-1773-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/5f6f223cdb10/CCR3-7-1773-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8012/6745376/0551d4e95f53/CCR3-7-1773-g003.jpg

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本文引用的文献

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CEN Case Rep. 2018 Nov;7(2):268-273. doi: 10.1007/s13730-018-0341-2. Epub 2018 May 25.
2
glomerular diseases after renal transplantation: How is it different from recurrent glomerular diseases?肾移植后的肾小球疾病：它与复发性肾小球疾病有何不同？
World J Transplant. 2017 Dec 24;7(6):285-300. doi: 10.5500/wjt.v7.i6.285.
3
De Novo IgA Nephropathy in a Renal Allograft.同种异体肾移植中的新发IgA肾病
Exp Clin Transplant. 2019 Aug;17(4):550-553. doi: 10.6002/ect.2016.0266. Epub 2017 Jun 28.
4
Two consecutive recurrences of crescentic immunoglobulin A nephropathy in a renal transplant recipient.一名肾移植受者新月体性免疫球蛋白A肾病连续两次复发。
Indian J Nephrol. 2016 Sep;26(5):376-378. doi: 10.4103/0971-4065.169565.
5
De novo glomerular diseases after renal transplantation.肾移植后新发肾小球疾病
Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1479-87. doi: 10.2215/CJN.12571213. Epub 2014 Apr 3.
6
The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient.KDIGO 肾小球肾炎实践指南：从（指南）字里行间看问题——针对个体患者的应用。
Kidney Int. 2012 Oct;82(8):840-56. doi: 10.1038/ki.2012.280. Epub 2012 Aug 15.
7
Acute cellular rejection.急性细胞排斥反应。
Iran J Kidney Dis. 2007 Oct;1(2):54-6.
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Ren Fail. 2008;30(6):611-6. doi: 10.1080/08860220802134516.
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