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股骨头切除标本的病理学评估:一项重要的质量保证程序。

Pathology Assessment of Femoral Head Resection Specimens: An Important Quality Assurance Procedure.

机构信息

From the Departments of Pathology and Anatomical Sciences (Dr Layfield) and Radiology (Dr Crim), University of Missouri, Columbia; University of Missouri School of Medicine, M2, Columbia (Mr Oserowsky); and the Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City (Dr Schmidt).

出版信息

Arch Pathol Lab Med. 2020 May;144(5):580-585. doi: 10.5858/arpa.2019-0128-OA. Epub 2019 Sep 20.

Abstract

CONTEXT.—: Decisions to perform hip arthroplasty rely on both radiographic and clinical findings. Radiologists estimate degree of osteoarthritis (OA) and document other findings. Arthroplasty specimens are sometimes evaluated by pathology.

OBJECTIVE.—: To determine the frequency of pathologic changes not recognized clinically.

DESIGN.—: Nine hundred fifty-three consecutive femoral head resections performed between January 2015 and June 2018, with recent radiologic and histologic study, were reviewed. We compared severity of OA reported by radiology and pathology. Findings unrecognized radiographically but recorded pathologically, and discrepancies between clinical diagnosis and pathology diagnosis, were tabulated.

RESULTS.—: Twenty-one cases of osteomyelitis were diagnosed radiographically or pathologically. Eight discrepancies were present. Fourteen osteomyelitis cases were recognized clinically. Pathology recognized 2 neoplasms missed radiographically. Avascular necrosis was diagnosed on pathology but not radiology in 25 cases, and 35 cases of avascular necrosis were seen radiographically but not pathologically. Osteoarthritis was graded both radiographically and pathologically from 0 to 3. Five hundred ninety-one of 953 cases (62%) were grade 3. Pathologists and radiologists had perfect agreement in 696 of 953 cases (73%). When grade of OA seen at pathology was correlated with surgeon, 2 groups of surgeons were detected: one with a low threshold for performance of hip arthroplasty (23%-28% low-severity OA) and the second with a high threshold (2%-5% low-severity OA).

CONCLUSIONS.—: Correlation between radiology and pathology diagnoses is high. Degree of OA present varies significantly between surgeons. Pathology discloses findings not recognized clinically.

摘要

背景

髋关节置换术的决策依赖于影像学和临床发现。放射科医生评估骨关节炎(OA)的程度并记录其他发现。关节置换标本有时由病理科评估。

目的

确定临床上未识别的病理变化的频率。

设计

回顾了 2015 年 1 月至 2018 年 6 月期间连续进行的 953 例股骨头切除术,近期进行了放射学和组织学研究。我们比较了放射学和病理学报告的 OA 严重程度。记录了影像学上未识别但病理学上记录的病变以及临床诊断与病理学诊断之间的差异。

结果

影像学或病理学诊断出 21 例骨髓炎。存在 8 个差异。临床上识别出 14 例骨髓炎病例。病理学识别出 2 例影像学遗漏的肿瘤。25 例病理学诊断为股骨头坏死,但影像学未发现,35 例影像学诊断为股骨头坏死,但病理学未发现。骨关节炎在影像学和病理学上从 0 到 3 分级。953 例中有 591 例(62%)为 3 级。病理学家和放射科医生在 953 例中有 696 例(73%)完全一致。当将病理学上观察到的 OA 分级与外科医生相关联时,发现了两组外科医生:一组进行髋关节置换术的门槛较低(23%-28%为轻度 OA),另一组门槛较高(2%-5%为轻度 OA)。

结论

放射学和病理学诊断之间具有高度相关性。外科医生之间存在明显的 OA 程度差异。病理学揭示了临床上未识别的发现。

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