Brown Zoe, Perry Michael, Killen Cameron, Schmitt Daniel, Wesolowski Michael, Brown Nicholas M
Loyola University Chicago Stritch School of Medicine, Maywood, IL, USA.
Department of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Hip Pelvis. 2022 Mar;34(1):56-61. doi: 10.5371/hp.2022.34.1.56. Epub 2022 Mar 7.
Histopathologic analysis of femoral head specimens following total hip arthroplasty (THA) is a routine practice that represents a significant use of health care resources. However, it occasionally results in discovery of undiagnosed hematopoietic malignancy and other discrepant diagnoses such as avascular necrosis. The purpose of this study was to determine the rate of discordant and discrepant diagnoses discovered from routine histopathological evaluation of femoral heads following THA and perform a cost analysis of this practice.
A review of patients undergoing primary THA between 2004-2017 was conducted. A comparison of the surgeon's preoperative and postoperative diagnosis, and the histopathologic diagnosis was performed. In cases where the clinical and histopathology differed, a review determined whether this resulted in a change in clinical management. Medicare reimbursement and previously published cost data corrected for inflation were utilized for cost calculations.
A review of 2,134 procedures was performed. The pathologic diagnosis matched the postoperative diagnosis in 96.0% of cases. Eighty-three cases (4.0%) had a discrepant diagnosis where treatment was not substantially altered. There was one case of discordant diagnosis where lymphoma was diagnosed and subsequently treated. The cost per discrepant diagnosis was $141,880 and per discordant diagnosis was $1,669 when using 100% Medicare reimbursement and Current Procedural Terminology (CPT) code combination 88304+88311.
Histopathologic analysis of femoral head specimens in THAs showed an association with high costs given the rarity of discordant diagnoses. Routine use of the practice should be at the discretion of individual hospitals with consideration for cost and utility thresholds.
全髋关节置换术(THA)后股骨头标本的组织病理学分析是一种常规操作,这代表了医疗保健资源的大量使用。然而,它偶尔会导致发现未被诊断的造血系统恶性肿瘤以及其他不一致的诊断,如缺血性坏死。本研究的目的是确定THA后股骨头常规组织病理学评估中发现的不一致和差异诊断的发生率,并对这种操作进行成本分析。
对2004年至2017年间接受初次THA的患者进行回顾。比较外科医生的术前和术后诊断以及组织病理学诊断。在临床和组织病理学不同的情况下,进行回顾以确定这是否导致临床管理的改变。使用医疗保险报销和先前公布的经通胀校正的成本数据进行成本计算。
对2134例手术进行了回顾。96.0%的病例中病理诊断与术后诊断相符。83例(4.0%)有差异诊断,但治疗未发生实质性改变。有1例不一致诊断,诊断为淋巴瘤并随后进行了治疗。当使用100%医疗保险报销和现行程序术语(CPT)代码组合88304 + 88311时,每个差异诊断的成本为141,880美元,每个不一致诊断的成本为1,669美元。
鉴于不一致诊断的罕见性,THA中股骨头标本的组织病理学分析显示出与高成本相关。该操作的常规使用应由各医院自行决定,并考虑成本和效用阈值。