Department of Radiology and Diagnostic Imaging, University of Alberta, University of Alberta Hospital, Edmonton, Alberta, Canada.
Department of Radiology and Diagnostic Imaging, University of Alberta, University of Alberta Hospital, Edmonton, Alberta, Canada.
Can Assoc Radiol J. 2019 Nov;70(4):388-393. doi: 10.1016/j.carj.2019.06.007. Epub 2019 Sep 17.
Guidelines and high-quality studies recommend using clinical decision-making (CDM) tools over clinical gestalt when evaluating a patient for pulmonary embolism. The purpose of this study is to investigate our computed tomography pulmonary angiogram (CTPA) utilization patterns and identify causal factors.
A retrospective cohort study of CTPA studies ordered by emergency physicians in January, April, July, and October 2017 was undertaken. All necessary information to categorize patients by Wells' score, revised Geneva score, and pulmonary embolism rule-out criteria (PERC) was collected. In addition, various bloodwork, chest radiograph, and computed tomography results were collected. This data was analysed by the Pearson chi-square test or Fisher's exact test for categorical data and independent-samples t test for continuous variables.
A total of 510 CTPA studies were performed, with a mean age was 61.6 and a 50.6% female population. 136 studies (26.7%) failed to appropriately follow any CDM tool. CDM tool failure rate was dependent on whether the study was ordered from a community (14.9%) or tertiary hospital (University of Alberta Hospital, 27.9% and Royal Alexandra Hospital, 24.6%) (P = .038). Of these 136 studies, 31 were low/moderate risk and the d-dimer was negative. The remainder were either PERC-negative or low/moderate risk without d-dimer performed. The cumulative positive pulmonary embolism rate was 12.5%. With utilization of a CDM tool, the positive pulmonary embolism rate was 15.0%, compared to 5.9% when using gestalt (P = .026).
This study confirms a high rate of CDM tool use failure, and a higher positive CTPA rate for CDM tools compared to clinical gestalt.
指南和高质量研究建议在评估疑似肺栓塞患者时使用临床决策(CDM)工具而非临床直觉。本研究旨在调查我们的 CT 肺动脉造影(CTPA)的使用模式并找出原因。
回顾性队列研究,纳入 2017 年 1 月、4 月、7 月和 10 月由急诊医师开的 CTPA 研究。收集所有必要信息,以根据 Wells 评分、修订版日内瓦评分和肺栓塞排除标准(PERC)对患者进行分类。此外,还收集了各种血液检查、胸部 X 线和 CT 结果。使用 Pearson 卡方检验或 Fisher 确切检验对分类数据进行分析,使用独立样本 t 检验对连续变量进行分析。
共进行了 510 次 CTPA 研究,平均年龄为 61.6 岁,女性占 50.6%。136 项研究(26.7%)未能正确遵循任何 CDM 工具。CDM 工具失败率取决于研究是在社区医院(14.9%)还是三级医院(阿尔伯塔大学医院,27.9%和亚历山德拉皇家医院,24.6%)下达的(P=0.038)。在这 136 项研究中,31 项为低/中度风险且 D-二聚体阴性。其余为 PERC 阴性或低/中度风险且未行 D-二聚体检查。累积阳性肺栓塞率为 12.5%。使用 CDM 工具时,阳性肺栓塞率为 15.0%,而使用临床直觉时为 5.9%(P=0.026)。
本研究证实了 CDM 工具使用失败率较高,且与临床直觉相比,CDM 工具的 CTPA 阳性率更高。