De Stefano G F, Rickards O, Biondi G, Steckel A, Dannewitz A, Walter H
Dipartimento di Biologia, Università Tor Vergata, Rome, Italy.
Gene Geogr. 1987 Aug;1(2):135-42.
A random sample of 686 unrelated subjects from Bari (Southern Italy) and Genoa (Northern Italy) provinces was studied for HP polymorphism. The correlation between the HP1 frequencies and geographical coordinates was studied for the populations of Italy, Europe, Middle East and Mediterranean basin. The results reveal the existence of a gradient of declining HP1 frequencies from north-west to south-east across Europe and the Middle East.
对来自意大利南部巴里省和意大利北部热那亚省的686名无亲缘关系的受试者进行了随机抽样,以研究HP多态性。研究了意大利、欧洲、中东和地中海盆地人群中HP1频率与地理坐标之间的相关性。结果显示,在欧洲和中东地区,HP1频率从西北向东南呈递减梯度分布。