Mitchell R J
Department of Genetics and Human Variation, La Trobe University, Melbourne, Australia.
Gene Geogr. 1988 Aug-Dec;2(2-3):123-7.
A total of 2003 donors from the island state of Tasmania, Australia, were investigated for association between the genetic polymorphisms, ABO and haptoglobin, HP. No interaction between phenotypes of the two systems was found, although the observed deficit of HP*1 in group O has also been noted in the neighbouring Victorian population. When the Tasmanian and Victorian samples were merged to give a large Australian sample (N = 4,211) again no association was found among the phenotypes. However, significant differences were observed in the distributions of both HP phenotypes and alleles between group O and non-O persons respectively.
对来自澳大利亚塔斯马尼亚岛州的2003名献血者进行了研究,以调查基因多态性ABO和触珠蛋白(HP)之间的关联。未发现这两个系统表型之间存在相互作用,尽管在邻近的维多利亚人群中也注意到O型血人群中HP*1的缺失。当将塔斯马尼亚和维多利亚的样本合并以形成一个大型澳大利亚样本(N = 4211)时,表型之间同样未发现关联。然而,分别在O型血人群和非O型血人群中观察到HP表型和等位基因分布存在显著差异。