Department of Anatomy, Faculty of Medicine, Bolu Abant Izzet Baysal University, Bolu, Turkey.
Department of Anatomy, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Ann Anat. 2020 Jan;227:151416. doi: 10.1016/j.aanat.2019.151416. Epub 2019 Sep 18.
The purpose of this study is to determine whether there are differences in proximal femur parameters of women subjected to menopause surgically or naturally. In this study, 10 parameters belonging to proximal femur of a total of 60 women cases of whom 30 had a mean age of 55.53 ± 4.57 years; body mass index, 33.06 ± 4.21 kg/m; menopause age, 48.10 ± 5.92; and menopause years, 7.50 ± 4.58; and who were subjected to natural menopause; and 30 women whose mean age was 56.10 ± 6.87 years; body mass index, 33.33 ± 3.76 kg/m; menopause age, 48.00 ± 4.64 years and menopause year, 8.10 ± 7.29; who were subjected to surgical menopause, and who did not use hormone replacement, were examined by radiography. Their anthropometric measurements, body compositions, blood hormone analyses (FSH, LH, estradiol, progesterone) and bone mineral densities (femur neck, femur total, lumbar t-score) were evaluated. It was found that there was no difference between surgical and natural menopause with respect to proximal femur parameters (p > 0.05). It was also found that FSH levels were high in the surgical menopause group and there were significant differences between the groups (p < 0.040). No significant difference was found even though bone mineral density t-score tests were lower in the surgical menopause group (p > 0.05). It was found that the difference in low bone mineral density level and high FSH values in the surgical menopause group do not have a relationship with proximal femur morphometry. It was determined that even though the women did not have ovaries, there was no difference between surgical menopause women and natural menopause women with respect to proximal femur morphometry.
本研究旨在确定接受手术或自然绝经的女性在股骨近端参数上是否存在差异。在这项研究中,共检查了 60 名女性的股骨近端 10 个参数,其中 30 名女性的平均年龄为 55.53±4.57 岁;体重指数为 33.06±4.21kg/m;绝经年龄为 48.10±5.92 岁;绝经年限为 7.50±4.58 年,她们经历的是自然绝经;另外 30 名女性的平均年龄为 56.10±6.87 岁;体重指数为 33.33±3.76kg/m;绝经年龄为 48.00±4.64 岁,绝经年限为 8.10±7.29 年,她们经历的是手术绝经,且未使用激素替代治疗。通过放射摄影对她们的人体测量学测量、身体成分、血液激素分析(FSH、LH、雌二醇、孕酮)和骨矿物质密度(股骨颈、股骨总、腰椎 t 评分)进行了评估。结果发现,手术绝经和自然绝经在股骨近端参数方面没有差异(p>0.05)。还发现手术绝经组的 FSH 水平较高,两组间存在显著差异(p<0.040)。尽管手术绝经组的骨矿物质密度 t 评分较低,但差异无统计学意义(p>0.05)。结果表明,手术绝经组低骨密度水平和高 FSH 值的差异与股骨近端形态学无关。确定即使女性没有卵巢,手术绝经女性与自然绝经女性在股骨近端形态学方面也没有差异。