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肠粘连导致腹腔镜前路结肠间 Roux-en-Y 胃旁路术后小肠梗阻发生率增加与系膜缺损的闭合有关:一项回顾性队列研究。

Closure of mesenteric defects is associated with a higher incidence of small bowel obstruction due to adhesions after laparoscopic antecolic Roux-en-y gastric bypass: A retrospective cohort study.

机构信息

Department of Digestive and Hepatobiliary/pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium.

Department of Digestive and Hepatobiliary/pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium. Electronic address: mathieu.d'

出版信息

Int J Surg. 2019 Nov;71:149-155. doi: 10.1016/j.ijsu.2019.09.017. Epub 2019 Sep 19.

Abstract

INTRODUCTION

Small bowel obstruction (SBO) is a frequent complication after laparoscopic Roux-en-y gastric bypass (LRYGB).

OBJECTIVES

We wanted to evaluate the effect of closure of the mesenteric defects on the incidence of SBO and postoperative complications after LRYGB. Furthermore, we wanted to identify possible risk factors for SBO.

METHODS

This study was a retrospective cohort study of 1364 patients who underwent a LRYGB between July 2003 and October 2015. Cohort 1 contained 724 patients in whom mesenteric defects were not closed. Cohort 2 contained 640 patients in whom mesenteric defects were closed. Main outcome parameters were the incidence of SBO and postoperative complications as well as potential risk factors for SBO.

RESULTS

Closure of the mesenteric defects was associated with a reduction in the incidence of SBO due to internal herniation (4.8% vs. 5.5, p = 0.02) but resulted in a higher incidence of SBO due to postoperative adhesions (4.8% vs. 1.7%, p = 0.004). Multivariate analysis identified smoking as a risk factor for SBO (p = 0.0187). We observed a higher incidence of late postoperative pain in cohort 2 (5.3% vs. 2.1%, p = 0.007).

CONCLUSION

Although closure of the mesenteric defects is associated with a lower incidence of SBO due to internal herniation, this effect is countered by a higher incidence of SBO due to postoperative adhesions. Smoking is an independent risk factor for SBO after LRYGB. Closure of the mesenteric defects is associated with a higher incidence of late postoperative pain.

摘要

引言

小肠梗阻(SBO)是腹腔镜 Roux-en-y 胃旁路术(LRYGB)后的常见并发症。

目的

我们旨在评估关闭肠系膜缺损对 LRYGB 后 SBO 发生率和术后并发症的影响。此外,我们还希望确定 SBO 的可能危险因素。

方法

这是一项回顾性队列研究,共纳入 1364 例于 2003 年 7 月至 2015 年 10 月期间接受 LRYGB 的患者。队列 1 包含 724 例未关闭肠系膜缺损的患者,队列 2 包含 640 例关闭肠系膜缺损的患者。主要观察指标为 SBO 的发生率和术后并发症,以及 SBO 的潜在危险因素。

结果

关闭肠系膜缺损与由于内疝引起的 SBO 发生率降低相关(4.8%比 5.5%,p=0.02),但由于术后粘连导致 SBO 的发生率增加(4.8%比 1.7%,p=0.004)。多变量分析确定吸烟是 SBO 的危险因素(p=0.0187)。我们观察到队列 2 中晚期术后疼痛的发生率较高(5.3%比 2.1%,p=0.007)。

结论

尽管关闭肠系膜缺损与由于内疝引起的 SBO 发生率降低相关,但这种效果被由于术后粘连引起的 SBO 发生率增加所抵消。吸烟是 LRYGB 后 SBO 的独立危险因素。关闭肠系膜缺损与晚期术后疼痛的发生率增加相关。

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