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匹兹堡的肾脏移植:经验与创新

Kidney transplantation in Pittsburgh: experience and innovations.

作者信息

Markus B H, Hakala T R, Tzakis A, Mitchell S, Marino I R, Gordon R D, Duquesnoy R J, Starzl T E

机构信息

Department of Surgery, University of Pittsburgh, Pennsylvania.

出版信息

Clin Transpl. 1987:141-54.

PMID:3154391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3008579/
Abstract
  1. The introduction of combined CsA and steroid treatment as the baseline immunosuppressive medication significantly enhanced the results of kidney transplantation in our series. But various other preexisting recipient or donor conditions may still have an important effect on kidney transplant survival and should not go unrecognized. 2. Living-related kidney transplants were almost totally abandoned at our institution. Reasons for this approach are the increased availability of cadaveric donor organs, the improved results with cadaveric transplants under CsA and the possible risks to the living donors. 3. Combined liver/kidney transplants have been shown to offer a favorable treatment modality for patients with endstage liver and renal failure. 4. A newly developed center-oriented Transplant Information Management System (TIMY) significantly facilitates the clinical and research tasks in our department. 5. An integrated, computerized scoring system for equitable allocation of donor organs has proven to be highly effective during routine clinical use.
摘要
  1. 将环孢素(CsA)和类固醇联合治疗作为基线免疫抑制药物引入,显著提高了我们系列肾移植的效果。但其他各种预先存在的受者或供者情况仍可能对肾移植存活产生重要影响,不应被忽视。2. 在我们机构,亲属活体肾移植几乎完全被放弃。采取这种做法的原因是尸体供体器官的可获得性增加、在环孢素治疗下尸体移植效果改善以及对活体供者可能存在的风险。3. 肝肾联合移植已被证明为终末期肝肾功能衰竭患者提供了一种良好的治疗方式。4. 新开发的以中心为导向的移植信息管理系统(TIMY)极大地便利了我们科室的临床和研究工作。5. 一个用于公平分配供体器官的综合计算机评分系统在常规临床使用中已被证明非常有效。

相似文献

1
Kidney transplantation in Pittsburgh: experience and innovations.匹兹堡的肾脏移植:经验与创新
Clin Transpl. 1987:141-54.
2
A decade of experience with renal transplantation in African-Americans.非裔美国人肾移植十年经验
Ann Surg. 2002 Dec;236(6):794-804; discussion 804-805. doi: 10.1097/00000658-200212000-00012.
3
Living donor transplants.活体供体移植。
Clin Transpl. 1995:363-77.
4
Multifactorial analysis of renal transplants reported to the United Network for Organ Sharing Registry.向器官共享联合网络登记处报告的肾移植多因素分析。
Clin Transpl. 1992:299-317.
5
Adult-size kidneys without acute tubular necrosis provide exceedingly superior long-term graft outcomes for infants and small children: a single center and UNOS analysis. United Network for Organ Sharing.无急性肾小管坏死的成人尺寸肾脏为婴幼儿提供了极其优异的长期移植效果:单中心及器官共享联合网络(UNOS)分析。器官共享联合网络
Transplantation. 2000 Dec 27;70(12):1728-36. doi: 10.1097/00007890-200012270-00012.
6
Renal transplantation in the UK and Republic of Ireland.英国和爱尔兰共和国的肾移植
Clin Transpl. 2000:105-13.
7
Annual trends and triple therapy--1991-2000.1991 - 2000年的年度趋势与三联疗法
Clin Transpl. 2001:247-69.
8
The UNOS Scientific Renal Transplant Registry--2000.美国器官共享联合网络科学肾脏移植登记处——2000年
Clin Transpl. 2000:1-18.
9
The UNOS scientific renal transplant registry. United Network for Organ Sharing.美国器官共享联合网络(UNOS)的科学肾脏移植登记处。
Clin Transpl. 1995:1-18.
10
Renal transplantation in cyclosporine-treated recipients at the Singapore General Hospital.新加坡中央医院接受环孢素治疗的肾移植受者
Clin Transpl. 1999:189-97.

引用本文的文献

1
Multiscreen serum analysis of highly sensitized renal dialysis patients for antibodies toward public and private class I HLA determinants. Implications for computer-predicted acceptable and unacceptable donor mismatches in kidney transplantation.对高度致敏的肾透析患者进行多屏血清分析,以检测针对公共和私有I类HLA决定簇的抗体。对肾移植中计算机预测的可接受和不可接受供体错配的影响。
Transplantation. 1990 Sep;50(3):427-37. doi: 10.1097/00007890-199009000-00014.

本文引用的文献

1
A multifactorial system for equitable selection of cadaver kidney recipients.一种用于公平选择尸体肾受体的多因素系统。
JAMA. 1987 Jun 12;257(22):3073-5.
2
Equitable allocation of extrarenal organs: with special reference to the liver.肾外器官的公平分配:特别提及肝脏
Transplant Proc. 1988 Feb;20(1):131-8.
3
Successful sequential liver-kidney transplantation in a patient with performed lymphocytotoxic antibodies.一名存在预存淋巴细胞毒抗体的患者成功接受序贯肝肾移植。
Transplant Proc. 1987 Feb;19(1 Pt 1):767-8.
4
Living donors: con.活体捐赠者:续
Transplant Proc. 1987 Feb;19(1 Pt 1):174-5.
5
The roles of sex, race, and ABO groups.
Clin Transpl. 1986:199-221.
6
Donor and recipient age effect.供体和受体年龄的影响。
Clin Transpl. 1986:189-97.