精索静脉曲张切除术的扩展适应症
Extended indications for varicocelectomy.
作者信息
Machen G Luke, Sandlow Jay I
机构信息
Department of Urology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
出版信息
F1000Res. 2019 Sep 3;8. doi: 10.12688/f1000research.19579.1. eCollection 2019.
Abstract
The relationship between varicoceles and subfertility is well-established, but recent evidence suggests that varicoceles may cause global testicular dysfunction. This has led to exploration into expanding the indications for varicocelectomy. This review examines the literature regarding varix ligation as a treatment for non-obstructive azoospermia, elevated DNA fragmentation, and hypogonadism.
摘要
精索静脉曲张与生育力低下之间的关系已得到充分证实，但最近的证据表明，精索静脉曲张可能导致睾丸整体功能障碍。这促使人们探索扩大精索静脉结扎术的适应症。本综述研究了有关将曲张静脉结扎术作为治疗非梗阻性无精子症、DNA碎片化增加和性腺功能减退的文献。
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Double-stranded sperm DNA damage is a cause of delay in embryo development and can impair implantation rates.双链精子 DNA 损伤是胚胎发育延迟的原因，并可能损害着床率。
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Hypogonadism is independently associated with varicocele repair in a contemporary cohort of men in the USA.在美国当代男性队列中，性腺功能减退与精索静脉曲张修复独立相关。
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