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剖宫产术后母胎输血与新生儿血细胞比容:常规方法与经胎盘切断术的比较

Fetomaternal Bleeding and Neonatal Hematocrit following Cesarean Delivery: Routine versus Transplacental Transection.

作者信息

Gregory Emily, Towers Craig V, van Nes Jaclyn, Shumard Kristina, Fortner Kim B, Weitz Beth

机构信息

Department of Obstetrics & Gynecology, Maternal-Fetal Medicine, University of Tennessee Medical Center, Knoxville, Tennessee.

出版信息

AJP Rep. 2019 Jul;9(3):e298-e301. doi: 10.1055/s-0039-1697654. Epub 2019 Sep 19.

Abstract

To evaluate fetomaternal bleeding following routine cesarean delivery compared with cesarean delivery involving transplacental transection.  A prospective cohort study evaluating cesarean delivery in which the placenta was transected (cases) versus controls (placenta not transected) from January 2016 to April 2018. A maternal Kleihauer-Betke's (KB) test and newborn hematocrit were performed shortly after delivery.  The rate of a positive KB test was not significantly different between cases (  = 31) and controls (  = 61) (19 vs. 14%; odds ratio [OR]: 1.44; 95% confidence interval [CI]: 0.46-4.49;  = 0.74). Median neonatal hematocrits were not different. However, the rate of newborn hematocrits <40% at delivery was higher in cases compared with controls (23 vs. 3%; OR: 8.90; 95% CI: 1.72-45.90;  = 0.005).  A cesarean requiring transplacental transection to accomplish delivery does not significantly increase the rate of fetomaternal bleeding but is associated with a higher likelihood of newborn hematocrit <40% at delivery.

摘要

评估常规剖宫产与经胎盘横断剖宫产术后的母胎输血情况。一项前瞻性队列研究,评估2016年1月至2018年4月期间胎盘被横断的剖宫产(病例组)与对照组(胎盘未横断)。产后不久进行母血Kleihauer-Betke(KB)试验和新生儿血细胞比容检测。病例组(n = 31)和对照组(n = 61)的KB试验阳性率无显著差异(19%对14%;优势比[OR]:1.44;95%置信区间[CI]:0.46 - 4.49;P = 0.74)。新生儿血细胞比容中位数无差异。然而,病例组分娩时新生儿血细胞比容<40%的比例高于对照组(23%对3%;OR:8.90;95% CI:1.72 - 45.90;P = 0.005)。为完成分娩而需要经胎盘横断的剖宫产不会显著增加母胎输血率,但与分娩时新生儿血细胞比容<40%的可能性较高有关。

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本文引用的文献

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Detection of fetomaternal hemorrhage.胎儿母体出血的检测。
Am J Hematol. 2012 Apr;87(4):417-23. doi: 10.1002/ajh.22255. Epub 2012 Jan 9.
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Fetomaternal hemorrhage in women undergoing elective cesarean section.择期剖宫产术中的母婴血液转移。
Acta Obstet Gynecol Scand. 2011 Mar;90(3):253-7. doi: 10.1111/j.1600-0412.2010.01045.x. Epub 2010 Dec 14.

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