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评估一种神经毒素作为治疗露龈笑的辅助治疗方式。

Evaluation of a Neurotoxin as an Adjunctive Treatment Modality for the Management of Gummy Smile.

作者信息

Gupta Neha, Kohli Sarvraj

机构信息

Department of Dermatology, NSCB Government Medical College, Jabalpur, Madhya Pradesh, India.

Consultant Orthodontist (Jabalpur Hospital and Research Centre), Jabalpur, Madhya Pradesh, India.

出版信息

Indian Dermatol Online J. 2019 Aug 28;10(5):560-563. doi: 10.4103/idoj.IDOJ_365_18. eCollection 2019 Sep-Oct.

DOI:10.4103/idoj.IDOJ_365_18
PMID:31544076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6743383/
Abstract

INTRODUCTION

Excessive gingival display while smiling mars facial aesthetics, this condition is referred to as "gummy smile" (GS). Available literature suggests that Botulinum toxin type A (BTX-A) is effective in the management of excessive gingival display by denervating hyperfunctional muscles. This study was conducted to statistically assess the effects of BTX-A for the management of GS.

MATERIALS AND METHODS

A total of 10 patients between the ages of 18-27 years were selected for this study, they received BTX-A (Botox; Allergan, Irvine, CA, USA) injections for reduction of excessive gingival display at "Yonsei point" on both sides. Gingival display was measured as the vertical distance from the zenith of the gingiva of the upper right central incisor to the inferior border of the upper lip before beginning treatment (T0). The patients were then recalled after 15 days to measure the gingival display (T1). Standardized photographs to document changes were obtained at T0 and T1.

RESULTS

A statistically significant reduction in gingival display, while smiling was observed from T0 (7.5 ± 1.35 mm) to T1 (3.2 ± 0.91 mm) in all 10 patients ( = 16.5168, value = 4.87, < 0.05).

CONCLUSIONS

Administration of BTX-A is recommended as an adjuvant to orthodontic treatment where the GS is caused due to hyperfunctional upper lip elevator muscles.

摘要

引言

微笑时牙龈过度暴露会破坏面部美观，这种情况被称为“牙龈微笑”（GS）。现有文献表明，A型肉毒杆菌毒素（BTX-A）通过使功能亢进的肌肉失神经支配，在治疗牙龈过度暴露方面是有效的。本研究旨在对BTX-A治疗GS的效果进行统计学评估。

材料与方法

本研究共选取了10名年龄在18至27岁之间的患者，他们接受了BTX-A（保妥适；美国艾尔建公司，加利福尼亚州欧文市）注射，以减少双侧“延世点”处的牙龈过度暴露。在开始治疗前（T0），测量牙龈暴露情况，即右上中切牙龈缘顶点至上唇下缘的垂直距离。然后在15天后召回患者测量牙龈暴露情况（T1）。在T0和T1时获取标准化照片以记录变化。

结果

在所有10名患者中，观察到微笑时牙龈暴露从T0（7.5±1.35毫米）到T1（3.2±0.91毫米）有统计学意义的显著降低（=16.5168， 值=4.87，<0.05）。

结论

对于因上唇提肌功能亢进导致的GS，建议将BTX-A作为正畸治疗的辅助手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/dd5a25916dab/IDOJ-10-560-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/9274b0e4bcf9/IDOJ-10-560-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/b7c8ada88ca7/IDOJ-10-560-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/dd5a25916dab/IDOJ-10-560-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/9274b0e4bcf9/IDOJ-10-560-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/b7c8ada88ca7/IDOJ-10-560-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2728/6743383/dd5a25916dab/IDOJ-10-560-g003.jpg

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本文引用的文献

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3
Severe gummy smile with class II malocclusion treated with LeFort I osteotomy combined with horseshoe osteotomy and intraoral vertical ramus osteotomy.采用LeFort I型截骨术联合马蹄形截骨术及口内垂直升支截骨术治疗伴有安氏II类错牙合的重度露龈笑。
Acta Med Okayama. 2013;67(1):55-60. doi: 10.18926/AMO/49257.
4
Botox as an adjunct to orthognathic surgery for a case of severe vertical maxillary excess.肉毒杆菌毒素作为正颌外科手术的辅助手段用于治疗一例严重垂直上颌骨过度生长病例。
J Maxillofac Oral Surg. 2011 Sep;10(3):266-70. doi: 10.1007/s12663-011-0178-0. Epub 2011 Feb 25.
5
Gummy smile and botulinum toxin: a new approach based on the gingival exposure area. Gummy 微笑和肉毒毒素：一种基于牙龈暴露面积的新方法。
J Am Acad Dermatol. 2010 Dec;63(6):1042-51. doi: 10.1016/j.jaad.2010.02.053.
6
Myotomy of the levator labii superioris muscle and lip repositioning: a combined approach for the correction of gummy smile.上唇提肌切开术和唇复位术：一种联合治疗露龈笑的方法。
Plast Reconstr Surg. 2010 Sep;126(3):1014-1019. doi: 10.1097/PRS.0b013e3181e3b6d4.
7
Botox and the gummy smile.肉毒杆菌毒素和笑龈。
Prog Orthod. 2010;11(1):76-82. doi: 10.1016/j.pio.2010.04.004. Epub 2010 May 25.
8
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9
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Am J Orthod Dentofacial Orthop. 2006 Nov;130(5):676-85. doi: 10.1016/j.ajodo.2005.07.013.
10
Anterior esthetic gingival depigmentation and crown lengthening: report of a case.前牙美学牙龈去色素沉着与牙冠延长术：病例报告
J Contemp Dent Pract. 2005 Aug 15;6(3):139-47.