Department of Cornea and Refractive Services, Aravind Eye Hospital, Madurai, Tamil Nadu, India.
London School of Hygiene and Tropical Medicine, London, United Kingdom.
Indian J Ophthalmol. 2019 Oct;67(10):1593-1598. doi: 10.4103/ijo.IJO_1821_18.
To understand demographic and socioeconomic barriers and treatment-seeking behaviors of patients with infectious keratitis requiring therapeutic penetrating keratoplasty (TPK) in a developing country.
This prospective non-comparative questionnaire- based study included all patients presenting to Aravind Eye Hospital, Madurai with infectious keratitis that eventuated to TPK between November 2015 and October 2016. A structured questionnaire was administered on post-operative day 3 to collect data on the demographic details, predisposing factors, prior treatment received, and treatment expenditures.
In total, 227 patients underwent TPK between November 2015 and October 2016 for infectious keratitis. The majority of patients were males (n = 132, 58.1%), illiterate (n = 129, 56.8%), and had a family monthly income of less than INR 6000 (n = 142, 62.5%). Most of the patients (n = 163, 71.8%) had prior treatment with an ophthalmologist before presenting to our hospital. The mean distance travelled to reach our centre was 269.2 ± 298.5 km. The mean duration of disease before the presentation was 20.3 ± 21.1 days. Corneal smear was positive for fungus in 163 (88.1%) and Aspergillus was the most commonly isolated fungi in 55 (41.3%) cultures. The mean total cost of treatment was INR 8752.87 ± 7615.39 per patient. There was a positive correlation between the duration of the disease (rho 0.19, P = 0.0034) and the costs of treatment (rho 0.2, P = 0.0024) with the distance travelled by the patient.
Patients who travelled a farther distance had a delayed onset of presentation and spent significantly more than their respective counterparts.
了解发展中国家需要进行治疗性穿透性角膜移植术(TPK)的感染性角膜炎患者的人口统计学和社会经济学障碍以及治疗寻求行为。
本前瞻性非对照问卷调查研究纳入了 2015 年 11 月至 2016 年 10 月期间在阿拉文眼科医院马杜赖就诊并因感染性角膜炎最终行 TPK 的所有患者。术后第 3 天,通过结构化问卷收集患者的人口统计学细节、易患因素、既往治疗和治疗费用。
2015 年 11 月至 2016 年 10 月期间,共有 227 例患者因感染性角膜炎行 TPK。大多数患者为男性(n=132,58.1%)、文盲(n=129,56.8%)和家庭月收入低于 INR 6000(n=142,62.5%)。大多数患者(n=163,71.8%)在来我院就诊前曾在眼科医生处接受过治疗。到达我们中心的平均距离为 269.2±298.5km。就诊前疾病的平均持续时间为 20.3±21.1 天。角膜刮片阳性的真菌有 163 例(88.1%),培养分离出的最常见真菌为曲霉,共 55 例(41.3%)。每位患者的平均总治疗费用为 INR 8752.87±7615.39。患者的疾病持续时间(rho 0.19,P=0.0034)和治疗费用(rho 0.2,P=0.0024)与患者的旅行距离呈正相关。
旅行距离较远的患者就诊时间较晚,花费也明显高于其他患者。