Synthesis, Physicochemical Properties, and Biological Activities of 4-(-Methyl--(2,2,2-Trifluoroacetyl)Sulfilimidoyl) Anthranilic Diamide.

Novel anthranilic diamides with sulfilimidoyl and sulfoximidoyl functionalities were successfully prepared. Among newly-prepared organosulfur compounds, 3-bromo-1-(3-chloropyridin-2-yl)--(2-methyl-6-(methylcarbamoyl)-4-(methylthio)phenyl)-1-pyrazole-5-carboxamide and (,)-3-bromo-1-(3-chloropyridin-2-yl)--(2-methyl-4-(S-methyl--(2,2,2-trifluoroacetyl)sulfinimidoyl)-6-(methylcarbamoyl)phenyl)-1-pyrazole-5-carboxamide showed good levels of efficacy and a strong correlation between insecticidal activities and physical properties, respectively. In particular, available data indicated that the -trifluoroacetyl sulfilimine moiety could be an appealing structural scaffold for the discovery of a new crop-protecting agent.