Aleris Obesity Clinic and Department of Surgery, Aleris Hospital, Oslo, Norway.
Aleris Obesity Clinic and Department of Surgery, Aleris Hospital, Oslo, Norway.
Surg Obes Relat Dis. 2019 Sep;15(9):1520-1526. doi: 10.1016/j.soard.2019.05.003. Epub 2019 May 13.
Long-term durability after Roux-en-Y gastric bypass is challenging in the super-obese population. Although lengthening of biliopancreatic limb (BPL) is associated with higher rates of weight loss, shortening of common limb (CL) is related to higher risk of malabsorption.
In this study, we aimed at evaluating the importance of the total alimentary limb length by creating a 2-m BPL diversion with varying CL lengths.
High-volume bariatric center, Norway.
Three groups of patients (N = 187) with different limb lengths were included in this retrospective cohort-analysis as follows: group 1 (n = 69; Roux limb = 150 cm, BPL = 60 cm), group 2 (n = 88; BPL = 200 cm, CL = 150 cm), and group 3 (n = 30; BPL = 200 cm, CL = 200 cm). Weight loss, regain, and failure were analyzed along with malabsorption issues.
Preoperative body mass index (BMI) was higher in group 2 (58.5, P < .001) and 3 (57.4) versus group 1 (54.6, P = .011). No other clinically significant differences between the groups were noted. Follow-up rate was 95% at year 2, 74% at year 5, and 52% at year 10. At 10-year follow-up, excess weight loss and total weight loss was higher in group 2 (70.4%; 40.3%) and 3 (64.0%; 35.9%) compared with group 1 (55.9%; 29.2%). Excess weight loss failure was higher in group 1 versus 2 (30% versus 8.3%, P < .001). No difference in short- or long-term complications was seen except higher occurrence of internal hernia in distal Roux-en-Y gastric bypass groups (11.4%, 6.7%). Vitamin and mineral deficiencies occurred more frequently the shorter the CL was.
Sustainable weight loss in a long-term follow-up is achieved by shortening the total alimentary limb length with a 2-m BPL diversion that should not be attached <200 cm from the ileocecal junction owing to higher rates of internal hernia and vitamin and mineral deficiencies.
罗伊恩-耶 gastric bypass 术后的长期耐久性在超级肥胖人群中具有挑战性。虽然延长胆胰支(BPL)与更高的减重率相关,但缩短共同支(CL)与更高的吸收不良风险相关。
在这项研究中,我们旨在通过创建具有不同 CL 长度的 2m BPL 分流来评估总肠支长度的重要性。
挪威大容量减重中心。
本回顾性队列分析纳入了三组不同肠支长度的患者(N=187):组 1(n=69;Roux 支=150cm,BPL=60cm),组 2(n=88;BPL=200cm,CL=150cm)和组 3(n=30;BPL=200cm,CL=200cm)。分析了减重、体重反弹和失败以及吸收不良问题。
组 2(58.5,P<.001)和 3(57.4)的术前体重指数(BMI)高于组 1(54.6,P=.011)。组间无其他显著临床差异。在第 2 年时的随访率为 95%,第 5 年时为 74%,第 10 年时为 52%。在 10 年随访时,组 2(70.4%;40.3%)和 3(64.0%;35.9%)的超重减重和总减重均高于组 1(55.9%;29.2%)。与组 2(8.3%,P<.001)相比,组 1 的超重减重失败率更高(30%)。除远端 Roux-en-Y gastric bypass 组的内部疝发生率较高(11.4%,6.7%)外,未见短期或长期并发症的差异。CL 越短,维生素和矿物质缺乏的发生率越高。
通过缩短 2m BPL 分流的总肠支长度,可以实现长期随访中的可持续减重,BPL 分流不应附着在回盲肠交界处<200cm 处,因为内部疝和维生素及矿物质缺乏的发生率较高。