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改进的蒙特卡罗临床电子束建模。

Improved Monte Carlo clinical electron beam modelling.

机构信息

Department of Medical Physics, Faculty of Health Sciences, University of the Free State, P.O. Box 339, Bloemfontein 9300, South Africa.

出版信息

Phys Med. 2019 Oct;66:36-44. doi: 10.1016/j.ejmp.2019.09.073. Epub 2019 Sep 21.

Abstract

PURPOSE

An EGSnrc based electron model was developed and validated for an Elekta Synergy® 160-leaf Agility™ linear accelerator. It was able to reproduce measured central axis (CAX) percentage depth dose (PDD) curves and off-axis profiles (OAPs) within 2%/2 mm, and relative output factors (ROFs) within 3%.

METHODS

BEAMnrc component modules were used to model the accelerator accurately according to vendor supplied specifications. The electron beam focal spot size and input energy spectrum were determined through their effects on electron CAX PDDs and OAPs as benchmarked against water tank data. Phase space files were used as source input in DOSXYZnrc water phantom simulations. Dose distributions were calculated for six electron nominal energies, 11 field sizes and two source-to-surface distances.

RESULTS

The full width at half maximum of the focal spot (assuming a Gaussian intensity distribution) was determined to be 1.50 mm. An asymmetrical input electron energy spectrum with a low-energy tail produced good agreement with measured data and solved the match in the build-up (BU) region for all electron energies used in this study.

CONCLUSIONS

The improved input electron spectra for the electron model could predict dose distributions within 2%/2 mm of measured data. The model's success is embedded in the asymmetrical energy spectrum which provided a valuable free parameter which, by fine adjustment, improved the match in the BU region of dose distributions. Furthermore, focal spot parameters could be determined by means of iterative simulations.

摘要

目的

为 Elekta Synergy® 160 叶 Agility™ 线性加速器开发并验证了基于 EGSnrc 的电子模型。该模型能够在 2%/2mm 内再现测量的中心轴(CAX)百分深度剂量(PDD)曲线和离轴曲线(OAPs),在 3%内再现相对输出因子(ROF)。

方法

根据供应商提供的规格,使用 BEAMnrc 组件模块准确地对加速器进行建模。通过它们对电子 CAX PDD 和 OAP 的影响来确定电子束焦点大小和输入能谱,作为与水箱数据对比的基准。相空间文件用作 DOSXYZnrc 水模体模拟中的源输入。针对六个电子标称能量、11 个射野大小和两个源皮距,计算了剂量分布。

结果

焦点的半高全宽(假设高斯强度分布)确定为 1.50mm。具有低能尾巴的不对称输入电子能谱与测量数据吻合良好,并解决了本研究中使用的所有电子能量的 buildup(BU)区域的匹配问题。

结论

电子模型中改进的输入电子能谱可以在 2%/2mm 内预测剂量分布。该模型的成功之处在于非对称能谱,它提供了一个有价值的自由参数,通过精细调整,改善了剂量分布的 BU 区域的匹配。此外,还可以通过迭代模拟确定焦点参数。

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