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利用 EGSnrc 蒙特卡罗系统开发适用于 CyberKnife VSI 系统的医用直线加速器头部模型。

Development of a LINAC head model for the CyberKnife VSI-System using EGSnrc Monte Carlo system.

机构信息

German CyberKnife-Center, Soest, Germany.

German Center for Stereotaxy and Precision Irradiation, Soest, Germany.

出版信息

J Appl Clin Med Phys. 2023 Dec;24(12):e14137. doi: 10.1002/acm2.14137. Epub 2023 Sep 15.

DOI:10.1002/acm2.14137
PMID:37712892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10691629/
Abstract

INTRODUCTION

In order to understand the interaction processes of photons and electrons of the CyberKnife VSI-System, a modeling of the LINAC head must take place. Here, a Monte Carlo simulation can help. By comparing the measured data with the simulation data, the agreement can be checked.

MATERIALS AND METHODS

For the Monte Carlo simulations, the toolkit EGSnrc with the user codes BEAMnrc and DOSXZYnrc was used. The CyberKnife VSI-System has two collimation systems to define the field size of the beam. On the one hand, it has 12 circular collimators and, on the other, an IRIS-aperture. The average energy, final source width, dose profiles, and output factors in a voxel-based water phantom were determined and compared to the measured data.

RESULTS

The average kinetic energy of the electron beam for the CyberKnife VSI LINAC head is 6.9 MeV, with a final source width of 0.25 cm in x-direction and 0.23 cm in y-direction. All simulated dose profiles for both collimation systems were able to achieve a global gamma criterion of 1%/1 mm to the measured data. For the output factors, the deviation from simulated to measured data is < 1% from a field size of 12.5 mm for the circular collimators and from a field size of 10 mm for the IRIS-aperture.

CONCLUSION

The beam characteristics of the CyberKnife VSI LINAC head could be exactly simulated with Monte Carlo simulation. Thus, in the future, this model can be used as a basis for electronic patient-specific QA or to determine scattering processes of the LINAC head.

摘要

引言

为了理解 CyberKnife VSI-System 的光子和电子相互作用过程,必须对直线加速器头进行建模。在这里,蒙特卡罗模拟可以提供帮助。通过将测量数据与模拟数据进行比较,可以检查一致性。

材料和方法

对于蒙特卡罗模拟,使用了 EGSnrc 工具包以及 BEAMnrc 和 DOSXZYnrc 用户代码。CyberKnife VSI-System 有两个准直系统来定义光束的射野大小。一方面,它有 12 个圆形准直器,另一方面,有一个 IRIS 光圈。在体素水模中,确定了平均能量、最终源宽度、剂量分布和输出因子,并将其与测量数据进行比较。

结果

CyberKnife VSI LINAC 头的电子束平均动能为 6.9 MeV,x 方向的最终源宽度为 0.25cm,y 方向为 0.23cm。两个准直系统的所有模拟剂量分布都能够达到 1%/1mm 的全局伽马标准,与测量数据相符。对于输出因子,从模拟到测量数据的偏差<1%,从圆形准直器的 12.5mm 射野到 IRIS 光圈的 10mm 射野。

结论

CyberKnife VSI LINAC 头的束特性可以通过蒙特卡罗模拟准确模拟。因此,在未来,该模型可以用作电子患者特定 QA 的基础,或用于确定 LINAC 头的散射过程。

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本文引用的文献

1
Beam modeling and beam model commissioning for Monte Carlo dose calculation-based radiation therapy treatment planning: Report of AAPM Task Group 157.基于蒙特卡罗剂量计算的放射治疗计划的束流建模和束流模型验证:AAPM 工作组 157 报告。
Med Phys. 2020 Jan;47(1):e1-e18. doi: 10.1002/mp.13898. Epub 2019 Nov 19.
2
Improved Monte Carlo clinical electron beam modelling.改进的蒙特卡罗临床电子束建模。
Phys Med. 2019 Oct;66:36-44. doi: 10.1016/j.ejmp.2019.09.073. Epub 2019 Sep 21.
3
Benchmarking Monte-Carlo dose calculation for MLC CyberKnife treatments.
MLC CyberKnife 治疗的 Monte-Carlo 剂量计算基准测试。
Radiat Oncol. 2019 Sep 18;14(1):172. doi: 10.1186/s13014-019-1370-5.
4
Dosimetry of small static fields used in external photon beam radiotherapy: Summary of TRS-483, the IAEA-AAPM international Code of Practice for reference and relative dose determination.外照射光子束放射治疗中应用的小静态场剂量学:IAEA-AAPM 国际实践导则 TRS-483 的摘要,用于参考和相对剂量确定。
Med Phys. 2018 Nov;45(11):e1123-e1145. doi: 10.1002/mp.13208. Epub 2018 Oct 17.
5
Independent Monte-Carlo dose calculation for MLC based CyberKnife radiotherapy.基于多叶准直器的 CyberKnife 放射治疗的独立蒙特卡罗剂量计算。
Phys Med Biol. 2017 Dec 19;63(1):015015. doi: 10.1088/1361-6560/aa97f8.
6
Characteristics and performance of the first commercial multileaf collimator for a robotic radiosurgery system.用于机器人放射外科系统的首款商用多叶准直器的特性与性能
Med Phys. 2016 May;43(5):2063. doi: 10.1118/1.4944740.
7
Report of AAPM TG 135: quality assurance for robotic radiosurgery.AAPM TG135 报告:机器人放射外科的质量保证。
Med Phys. 2011 Jun;38(6):2914-36. doi: 10.1118/1.3579139.
8
The design, physical properties and clinical utility of an iris collimator for robotic radiosurgery.用于机器人放射外科手术的虹膜准直器的设计、物理特性及临床应用
Phys Med Biol. 2009 Sep 21;54(18):5359-80. doi: 10.1088/0031-9155/54/18/001. Epub 2009 Aug 18.
9
Total scatter factors of small beams: a multidetector and Monte Carlo study.小射野的总散射因子:多探测器与蒙特卡洛研究
Med Phys. 2008 Feb;35(2):504-13. doi: 10.1118/1.2828195.
10
Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning.美国医学物理师协会第105任务组报告:基于蒙特卡罗方法的光子和电子外照射治疗计划临床实施相关问题
Med Phys. 2007 Dec;34(12):4818-53. doi: 10.1118/1.2795842.