Kwon Miseon, Lee Jae-Hong
Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
J Mov Disord. 2019 Sep;12(3):152-160. doi: 10.14802/jmd.19048. Epub 2019 Sep 30.
Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson's disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably due to poor the self-awareness of the conditions and the underuse of validated tools and objective instruments for assessment. The early detection and intervention of dysphagia are closely related to improving the quality of life and decreasing the mortality rate in these patients. The purpose of this paper is to give an overview of the characteristics of dysphagia, including the epidemiology, pathophysiology, and clinical symptomatology, in patients with PD compared with other parkinsonian disorders and movement disorders. The management of dysphagia and future research directions related to these disorders are also discussed.
口咽吞咽困难是帕金森病(PD)及相关疾病患者的常见症状,即使在疾病早期也是如此。这些患者的吞咽困难可能未得到充分诊断,这可能是由于患者对病情的自我认知不足,以及用于评估的有效工具和客观仪器使用不足。吞咽困难的早期发现和干预与改善这些患者的生活质量及降低死亡率密切相关。本文旨在概述与其他帕金森病及运动障碍相比,PD患者吞咽困难的特征,包括流行病学、病理生理学和临床症状学。还讨论了吞咽困难的管理以及与这些疾病相关的未来研究方向。
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