Pharmacy Department, Merit Health Central Hospital, Jackson, Mississippi.
JMS Burn and Reconstruction Center, Merit Health Central Hospital, Jackson, Mississippi.
Surg Infect (Larchmt). 2020 Mar;21(2):158-160. doi: 10.1089/sur.2019.067. Epub 2019 Sep 26.
Infections with spp. are a recognized complication of leech therapy for circulatory complications in replanted digits. Ciprofloxacin is commonly used empirically for coverage in such cases. Evolving resistance patterns of should be considered in designing an antibiotic strategy. Three consecutive patients with complicated replantations had site cultures yielding isolates resistant to ciprofloxacin. These cultures were analyzed to identify effective antibiotic agents. Each isolate, and each additional site organism, was sensitive to cefepime. Our routine antibiotic coverage for leech application has been changed to cefepime. sensitivities and resistances should be monitored to adapt to future changes in appropriate antibiotics.
感染 spp. 是由于使用医用水蛭治疗再植手指的循环并发症而引起的一种公认的并发症。在这种情况下，通常会经验性地使用环丙沙星来覆盖治疗。在制定抗生素策略时，应考虑到 不断变化的耐药模式。连续三位患有复杂再植术的患者的局部培养物产生了对环丙沙星耐药的 分离株。对这些培养物进行了分析，以确定有效的抗生素药物。每个 分离株，以及每个其他部位的生物体，都对头孢吡肟敏感。我们医用水蛭应用的常规抗生素覆盖范围已更改为头孢吡肟。应监测 的敏感性和耐药性，以适应未来适当抗生素的变化。
