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一次癫痫发作，不要发芽：海马苔藓纤维发芽在癫痫中的作用。

One Seizure Please, Hold the Sprouts: The Role of Hippocampal Mossy Fiber Sprouting in Epilepsy.

作者信息

Beenhakker Mark, Ritger Matthew

出版信息

Epilepsy Curr. 2019 Nov-Dec;19(6):414-416. doi: 10.1177/1535759719876556. Epub 2019 Sep 26.

DOI:10.1177/1535759719876556
PMID:31558042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6891178/
Abstract

[Box: see text].

摘要

[方框：见正文]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/6891178/7ce6f76924b2/10.1177_1535759719876556-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/6891178/7ce6f76924b2/10.1177_1535759719876556-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb1/6891178/7ce6f76924b2/10.1177_1535759719876556-fig1.jpg

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本文引用的文献

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Effect of adenosine on short-term synaptic plasticity in mouse piriform cortex in vitro: adenosine acts as a high-pass filter.腺苷对体外培养的小鼠梨状皮层短期突触可塑性的影响：腺苷起高通滤波器的作用。
Physiol Rep. 2019 Feb;7(3):e13992. doi: 10.14814/phy2.13992.
2
Advances in understanding hilar mossy cells of the dentate gyrus.齿状回门区苔藓细胞研究进展
Cell Tissue Res. 2018 Sep;373(3):643-652. doi: 10.1007/s00441-017-2750-5. Epub 2017 Dec 8.
3
Short-Term Depression of Sprouted Mossy Fiber Synapses from Adult-Born Granule Cells.
成年新生颗粒细胞发芽苔藓纤维突触的短期抑制
J Neurosci. 2017 Jun 7;37(23):5722-5735. doi: 10.1523/JNEUROSCI.0761-17.2017. Epub 2017 May 11.
4
Plasticity-dependent, full detonation at hippocampal mossy fiber-CA3 pyramidal neuron synapses.可塑性依赖的海马苔藓纤维 - CA3 锥体神经元突触处的完全引爆。
Elife. 2016 Oct 25;5:e17977. doi: 10.7554/eLife.17977.
5
Does mossy fiber sprouting give rise to the epileptic state?苔藓纤维出芽会引发癫痫状态吗？
Adv Exp Med Biol. 2014;813:161-8. doi: 10.1007/978-94-017-8914-1_13.
6
High-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy.高剂量雷帕霉素阻断颞叶癫痫小鼠模型中苔藓纤维发芽，但不能阻止癫痫发作。
Epilepsia. 2013 Sep;54(9):1535-41. doi: 10.1111/epi.12246. Epub 2013 Jul 12.
7
Short-term presynaptic plasticity.短期突触前可塑性。
Cold Spring Harb Perspect Biol. 2012 Jul 1;4(7):a005702. doi: 10.1101/cshperspect.a005702.
8
Dendritic computation.树突状计算
Annu Rev Neurosci. 2005;28:503-32. doi: 10.1146/annurev.neuro.28.061604.135703.
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Temporal lobe tumoral epilepsy: characteristics and predictors of surgical outcome.颞叶肿瘤性癫痫：手术结果的特征及预测因素
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10
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