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综合征性和神经肌肉型脊柱侧弯手术后的特发性中风:一例病例报告及文献综述

Idiopathic stroke after syndromic and neuromuscular scoliosis surgery: a case report and literature review.

作者信息

Nguyen Thomas, Khanna Krishn, Gornitzky Alex L, Diab Mohammad

机构信息

School of Medicine, University of California - San Francisco, San Francisco, CA 94158, USA.

Department of Orthopaedic Surgery, University of California - San Francisco, San Francisco, CA 94158, USA.

出版信息

AME Case Rep. 2019 Aug 6;3:28. doi: 10.21037/acr.2019.07.07. eCollection 2019.

Abstract

Children with syndromic and neuromuscular scoliosis undergoing corrective surgery experience higher complication rates than those with idiopathic scoliosis. A rare but devastating complication is stroke, which occurs in 0.57% of operations for neuromuscular scoliosis but accounts for 7.6% of deaths. Comorbidities associated with non-idiopathic scoliosis that increase risk of stroke include hypercoagulability, cardiac dysfunction, and contractures, which interfere with positioning and risk vascular compromise. Syndromic and neuromuscular diseases may predispose patients to intraoperative dural tears, either primarily (e.g., dural ectasia) or secondarily, in particular due to severity of deformity. We present the case of a perioperative, idiopathic stroke in a 15-year-old boy with scoliosis in the setting of neurofibromatosis type I, reviewing possible causes as well as strategies for preoperative assessment and postoperative monitoring.

摘要

患有综合征性和神经肌肉性脊柱侧弯并接受矫正手术的儿童,其并发症发生率高于特发性脊柱侧弯儿童。一种罕见但极具破坏性的并发症是中风,在神经肌肉性脊柱侧弯手术中,中风发生率为0.57%,但占死亡病例的7.6%。与非特发性脊柱侧弯相关的、增加中风风险的合并症包括高凝状态、心脏功能障碍和挛缩,这些会干扰体位摆放并增加血管受压风险。综合征性和神经肌肉性疾病可能使患者术中硬脊膜撕裂的风险增加,这种情况可能是原发性的(如硬脊膜扩张),也可能是继发性的,尤其是由于畸形严重程度所致。我们报告了一例15岁患有I型神经纤维瘤病并伴有脊柱侧弯的男孩围手术期发生特发性中风的病例,回顾了可能的病因以及术前评估和术后监测策略。

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