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[食源性病原体群体感应分子的检测与建模研究进展]

[Progress in detection and modeling of quorum sensing molecules of foodborne pathogens].

作者信息

He Weijia, Yue Siyuan, Wang Xiang, Sun Tianmei, Dong Qingli

机构信息

School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2019 Sep 25;35(9):1707-1714. doi: 10.13345/j.cjb.190061.

Abstract

Quorum sensing (QS) plays a major role in the outbreak mechanism of foodborne diseases caused by food poisoning and food spoilage. QS affects the formation of cell membrane and pathogenicity ofpathogenic bacteria. Through the in-depth understanding of QS molecules of food-borne pathogens, we describe here the types of signal molecules produced by Gram-negative and Gram-positive bacteria, and the differences in QS molecules. Meanwhile, we introduce the detection of QS molecules by different technologies. According to the influence of QS on food, we propose also future research needs for the control of foodborne pathogenic bacteria.

摘要

群体感应(QS)在由食物中毒和食物腐败引起的食源性疾病爆发机制中起着主要作用。群体感应影响细胞膜的形成和病原菌的致病性。通过深入了解食源性病原体的群体感应分子,我们在此描述革兰氏阴性菌和革兰氏阳性菌产生的信号分子类型以及群体感应分子的差异。同时,我们介绍了通过不同技术对群体感应分子的检测。根据群体感应对食物的影响,我们还提出了未来控制食源性病原体的研究需求。

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