Perry D J, Weiss R B, Hoth D F
Cancer Treat Rep. 1985 Feb;69(2):199-201.
Five cases of hypersensitivity reactions to amsacrine are reported. These five cases are compared to the three cases previously published. Sixty-two reports on the clinical use of amsacrine in a variety of solid tumors and hematological malignancy were reviewed. Nine cases of hypersensitivity were described in the 2095 patients reported in these clinical trials. The approximate incidence of hypersensitivity to amsacrine is 0.4%.
报告了5例对安吖啶的过敏反应。将这5例与之前发表的3例进行了比较。回顾了62篇关于安吖啶在各种实体瘤和血液系统恶性肿瘤临床应用的报告。在这些临床试验报告的2095例患者中描述了9例过敏反应。安吖啶过敏反应的大致发生率为0.4%。
