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经皮腔内冠状动脉成形术患者的随访临床结果。

Follow-up clinical results in patients undergoing percutaneous transluminal coronary angioplasty.

作者信息

Mabin T A, Holmes D R, Smith H C, Vlietstra R E, Reeder G S, Bresnahan J F, Bove A A, Hammes L N, Elveback L R, Orszulak T A

出版信息

Circulation. 1985 Apr;71(4):754-60. doi: 10.1161/01.cir.71.4.754.

Abstract

Complete follow-up data were obtained from 229 consecutive patients who underwent percutaneous transluminal coronary angioplasty (PTCA) between 1979 and 1982 (mean follow-up 14 months, range 6 to 37). Single-vessel disease was present in 143 and multivessel disease in 86. PTCA was successful in 153 patients (67%). Failure was followed initially by bypass surgery in 59 and by continued medical therapy in 17. After successful PTCA, 90% of patients were improved subjectively and 74% were asymptomatic at follow-up. After unsuccessful PTCA but prompt bypass, 90% were improved subjectively and 85% were asymptomatic. Among the 229 patients, 39 (17%) required an additional intervention because of angina during follow-up; 15 of these had repeat PTCA and 18 had bypass surgery. Among patients with successful PTCA, revascularization was complete in 77% and partial in 23%. The completeness of revascularization with PTCA had a significant impact on follow-up. The follow-up data of patients with successful single-vessel PTCA and of those with multivessel disease with complete revascularization were similar. When the patients with complete revascularization were compared with those with multivessel disease but incomplete revascularization, the follow-up data were characterized by a higher incidence of angina or need for bypass surgery in the latter group (63%) than in the former group (29%); those with incomplete revascularization also had a significantly reduced event-free survival.

摘要

从1979年至1982年间连续接受经皮腔内冠状动脉成形术(PTCA)的229例患者中获得了完整的随访数据(平均随访14个月,范围6至37个月)。单支血管病变患者143例,多支血管病变患者86例。PTCA在153例患者中成功(67%)。失败后,最初59例接受搭桥手术,17例继续药物治疗。PTCA成功后,90%的患者主观症状改善,随访时74%无症状。PTCA未成功但迅速进行搭桥手术后,90%的患者主观症状改善,85%无症状。在这229例患者中,39例(17%)在随访期间因心绞痛需要再次干预;其中15例接受了重复PTCA,18例接受了搭桥手术。在PTCA成功的患者中,血管重建完全的占77%,部分重建的占23%。PTCA血管重建的完整性对随访有显著影响。单支血管PTCA成功患者与多支血管病变且血管重建完全患者的随访数据相似。将血管重建完全的患者与多支血管病变但血管重建不完全的患者进行比较时,后一组(63%)心绞痛或需要搭桥手术的发生率高于前一组(29%);血管重建不完全的患者无事件生存率也显著降低。

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