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接受经皮腔内冠状动脉成形术患者的长期血管造影随访、心脏事件及生存率

Long-term angiographic follow up, cardiac events, and survival in patients undergoing percutaneous transluminal coronary angioplasty.

作者信息

Ernst S M, van der Feltz T A, Bal E T, van Bogerijen L, van den Berg E, Ascoop C A, Plokker H W

出版信息

Br Heart J. 1987 Mar;57(3):220-5. doi: 10.1136/hrt.57.3.220.

Abstract

The results of percutaneous transluminal coronary angioplasty were studied in 1352 consecutive patients. The angioplasty procedure was angiographically successful in 1163 (86%) patients and the success rate increased gradually with time. There were no significant differences in success rates in different vessels or indications. The success rate for repeat coronary angioplasty was 92%. In 85% of the patients the clinical course was uncomplicated. Myocardial infarction occurred in 3.6%, emergency coronary bypass grafting in 2.6%, elective bypass surgery in 4.6%, and there were 10 deaths (0.7%). There were 16 deaths (10 non-cardiac) during follow up in the 1163 patients in whom the first procedure was successful. Actuarial analysis showed that after a first angioplasty 77.9% remained free of symptoms and cardiac events for five years and that after a second angioplasty 76% did so. Angiographic follow up showed restenosis in 24% of patients but the overall clinical success rate was 86.2%. On the basis of the intention to treat the procedure was successful in 74.3% of all 1352 patients. Coronary artery bypass surgery was eventually performed in 11.6% of all patients. The long term angiographic success rate of coronary angioplasty is higher than previously suggested.

摘要

对1352例连续患者进行了经皮腔内冠状动脉成形术的研究。血管造影显示,1163例(86%)患者的血管成形术成功,成功率随时间逐渐提高。不同血管或适应证的成功率无显著差异。重复冠状动脉成形术的成功率为92%。85%的患者临床过程无并发症。心肌梗死发生率为3.6%,急诊冠状动脉搭桥术为2.6%,择期搭桥手术为4.6%,死亡10例(0.7%)。在首次手术成功的1163例患者随访期间,有16例死亡(10例非心脏原因)。精算分析显示,首次血管成形术后,77.9%的患者5年无症状且无心脏事件发生;第二次血管成形术后,这一比例为76%。血管造影随访显示,24%的患者出现再狭窄,但总体临床成功率为86.2%。基于意向性分析,1352例患者中74.3%的手术成功。最终,11.6%的患者接受了冠状动脉搭桥手术。冠状动脉成形术的长期血管造影成功率高于此前报道。

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