一项随机临床试验中通用黏合剂 12 个月后的临床和 OCT 结果。

Clinical and OCT outcomes of a universal adhesive in a randomized clinical trial after 12 months.

机构信息

Department of Cariology, Endodontology and Periodontology, University of Leipzig, Liebigstraße 12, 04103 Leipzig, Germany.

Institute for Medical Informatics, Statistics and Epidemiology (IMISE), Härtelstraße 16-18, 04107 Leipzig, University of Leipzig, Germany.

出版信息

J Dent. 2019 Nov;90:103200. doi: 10.1016/j.jdent.2019.103200. Epub 2019 Sep 25.

DOI:10.1016/j.jdent.2019.103200

PMID:31562889

Abstract

OBJECTIVES

To assess the performance of a universal adhesive in different application modes in non-carious cervical lesions clinically and by optical coherence tomography (OCT).

METHODS

55 adult patients with three non-carious cervical lesions (NCCL) each participated in the study. Lesions were restored with Scotchbond™ Universal (SBU, 3 M) applied in the self-etch (SBU-SE) and the selective-enamel-etch mode (SBU-SEE) in combination with Filtek™ Supreme XTE (3 M). OptiBond™ FL (OFL, Kerr) was used as a control. Restorations were clinically assessed (FDI criteria) after 14 days, 6 and 12 months and in parallel imaged by OCT (interfacial adhesive defects), starting immediately after filling placement. Cumulative failure rates (CFR) and means of interfacial adhesive defect were statistically evaluated.

RESULTS

After 12 months, CFRs were lower in the SBU groups (0.0% each) than in the OFL group (20.0%, p = 0.001). Clinically, small marginal fractures occurred three times more often in the SBU-SE than in the SBU-SEE group (p = 0.001). Immediately after filling placement and at each reassessment OCT revealed more interfacial defects at enamel interfaces for SBU/SE compared to SBU/SEE and OFL (p ≤ 0.044). At dentin/cement more defects were seen with OFL compared to SBU/SE and SBU/SEE (p ≤ 0.001). Before restoration loss, more interfacial defects appeared compared to remaining restorations (p = 0.132/0.002).

CONCLUSIONS

Clinical evaluation and OCT imaging revealed higher interfacial integrity for SBU in both application modes compared to OFL. OCT detected interfacial bond failures prior to clinical deterioration or restoration loss.

CLINICAL SIGNIFICANCE

Scotchbond Universal showed an equivalent or improved bonding performance compared to the reference adhesive. Selective enamel etching is recommended. The parameter interfacial adhesive defect seems to be a valuable predictor for evaluation of adhesive restoration systems.

摘要

目的

通过临床评估和光相干断层扫描（OCT）评估一种通用型粘结剂在非龋性颈面缺损（NCCL）中的不同应用模式的性能。

方法

研究纳入了 55 名成年患者，每位患者有 3 处 NCCL。病变采用 Scotchbond™ Universal（SBU，3M）进行修复，分别采用自酸蚀（SBU-SE）和选择性釉质酸蚀（SBU-SEE）模式，并结合 Filtek™ Supreme XTE（3M）。OptiBond™ FL（OFL， Kerr）为对照组。14 天、6 个月和 12 个月时采用 FDI 标准进行临床评估，并在即刻充填后采用 OCT 进行平行成像（界面粘结缺陷）。采用累积失败率（CFR）和界面粘结缺陷均值进行统计学评估。

结果

12 个月时，SBU 组的 CFR 更低（各为 0.0%），明显低于 OFL 组（20.0%，p=0.001）。临床检查发现，SBU-SE 组的微小边缘裂缝发生率比 SBU-SEE 组高 3 倍（p=0.001）。即刻充填后及每次重新评估时，OCT 显示 SBU/SE 组釉质界面的界面缺陷多于 SBU/SEE 和 OFL（p≤0.044）。与 SBU/SEE 和 SBU/SEE 相比，OFL 在牙本质/牙骨质处的界面缺陷更多（p≤0.001）。在修复体丧失前，与保留的修复体相比，界面缺陷更多（p=0.132/0.002）。