可能由万古霉素引起的中性粒细胞减少症：一例报告。

Probable Vancomycin Induced Neutropenia: A Case Report.

作者信息

Kaur Anahat, Khan Ghazal, Grover Punita, Moormeier Jill

机构信息

Internal Medicine, University of Missouri - Kansas City School of Medicine, Kansas City, USA.

Hematology and Oncology, University of Cincinnati, Cincinnati, USA.

出版信息

Cureus. 2019 Jul 22;11(7):e5199. doi: 10.7759/cureus.5199.

DOI:10.7759/cureus.5199

PMID:31565605

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6758989/

Abstract

Vancomycin has been used for a long time to manage resistant gram-positive bacterial infections. Neutropenia is an uncommon and potentially serious adverse effect associated with vancomycin use. Herein we present a case of probable vancomycin induced neutropenia which resolved with discontinuation of the antibiotic. Since blood counts are monitored routinely these days in both outpatient and inpatient setting, due consideration needs to be given to vancomycin induced neutropenia in patients who are on long term antimicrobial therapy.

摘要

万古霉素长期以来一直用于治疗耐药革兰氏阳性菌感染。中性粒细胞减少是与使用万古霉素相关的一种罕见且可能严重的不良反应。在此，我们报告一例可能由万古霉素引起的中性粒细胞减少病例，该病例在停用抗生素后得以缓解。由于如今在门诊和住院环境中都会常规监测血细胞计数，对于长期接受抗菌治疗的患者，需要充分考虑万古霉素引起的中性粒细胞减少。