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唾液α淀粉酶作为患病犬应激生物标志物的研究

Salivary alpha-amylase as a stress biomarker in diseased dogs.

作者信息

Hong Hwa Ran, Oh Ye In, Kim Young Jun, Seo Kyoung Won

机构信息

Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Korea.

BioMedIT Group, Electronics and Telecommunications Research Institute, Daejeon 34129, Korea.

出版信息

J Vet Sci. 2019 Sep;20(5):e46. doi: 10.4142/jvs.2019.20.e46.

Abstract

Salivary alpha-amylase (sAA) is a stress biomarker in human diseases, but there are no reports of sAA measurements in diseased dogs. This study measured the sAA and serum alpha-amylase (AA) levels in 16 healthy dogs and 31 diseased dogs using a kinetic enzyme assay to assess the stress status. The sAA and serum AA levels were significantly higher in the diseased dogs than in healthy dogs ( < 0.05), but there was no correlation between the 2 groups ( = 0.251, = 0.089). This suggests that sAA can be useful as a stress biomarker in diseased dogs.

摘要

唾液α-淀粉酶(sAA)是人类疾病中的一种应激生物标志物,但尚无关于患病犬sAA测量的报道。本研究采用动力学酶法测定了16只健康犬和31只患病犬的sAA和血清α-淀粉酶(AA)水平,以评估应激状态。患病犬的sAA和血清AA水平显著高于健康犬(<0.05),但两组之间无相关性(=0.251,=0.089)。这表明sAA可作为患病犬应激生物标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b85/6769321/3420be738c0f/jvs-20-e46-g001.jpg

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