From the Departments of Anesthesiology, Perioperative and Pain Medicine.
Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Anesth Analg. 2020 May;130(5):e119-e122. doi: 10.1213/ANE.0000000000004424.
Postpartum hemorrhage (PPH) is a leading cause of morbidity and mortality in the United States; its prevalence increased during the 1990s-2000s. The purpose of this study was to reevaluate trends in PPH using the National Inpatient Sample. From 2010 to 2014, the prevalence of PPH increased from 2.9% (95% confidence interval [CI], 2.7%-3.1%) to 3.2% (95% CI, 3.1%-3.3%) of deliveries. Adjusting for PPH risk factors did not substantially attenuate this trend. Among patients with PPH, there was a decline in associated coagulopathy, acute respiratory failure, and maternal death, but an increase in sepsis and acute renal failure. Continued focus on PPH management is warranted.
产后出血(PPH)是美国发病率和死亡率的主要原因;其患病率在 20 世纪 90 年代至 21 世纪初有所上升。本研究旨在利用国家住院患者样本重新评估 PPH 的趋势。从 2010 年到 2014 年,PPH 的患病率从分娩的 2.9%(95%置信区间[CI],2.7%-3.1%)增加到 3.2%(95%CI,3.1%-3.3%)。调整 PPH 风险因素并没有显著减弱这一趋势。在患有 PPH 的患者中,相关凝血功能障碍、急性呼吸衰竭和产妇死亡的发生率有所下降,但败血症和急性肾衰竭的发生率有所上升。需要继续关注 PPH 的管理。