McCarthy Michael H, Singh Partik, Maslak Joseph, Nayak Rusheel, Jenkins Tyler J, Hsu Wellington K, Patel Alpesh A
Department of Orthopaedic Surgery, Northwestern University.
Department of Orthopaedic Surgery, Northwestern Feinberg School of Medicine, Chicago, IL.
Clin Spine Surg. 2019 Nov;32(9):357-362. doi: 10.1097/BSD.0000000000000890.
This was a retrospective cohort study.
The objective of this study was to assess the American College of Surgeons (ACS) Risk Calculator's ability to accurately predict complications after cervical spine surgery.
Surgical risk calculators exist in many fields and may assist in the identification of patients at increased risk for complications and readmissions. Risk calculators may allow for improved outcomes, an enhanced informed consent process, and management of modifiable risk factors. The American College of Surgeons National Surgery Quality Improvement Program (ACS NSQIP) Risk Calculator was developed from a cohort of over 1.4 million patients, using 2805 unique Current Procedural Terminology (CPT) codes. The risk calculator uses 21 patient predictors (eg, age, American Society of Anesthesiologists class, body mass index, hypertension) and the planned procedure (CPT code) to predict the chance that patients will have any of 12 different outcomes (eg, death, any complication, serious complication, reoperation) within 30 days following surgery. The purpose of this study is to determine if the ACS NISQIP risk calculator can predict 30-day complications after cervical fusion.
A retrospective chart review was performed on patients that underwent primary cervical fusions between January 2009 and 2015 at a single institution, utilizing cervical fusion CPT codes. Patients without 30 days of postoperative follow-up were excluded. Descriptive statistics were calculated for the overall sample, anterior versus posterior fusion, and single versus multilevel fusion. Logistic regression models were fit with actual complication occurrence as the dependent variable in each model and ACS estimated risk as the independent variable. The c-statistic was used as the measure of concordance for each model. Receiver operating characteristic curves were plotted to visually depict the predictive ability of the estimated risks. Acceptable concordance was set at c>0.80. All analyses were conducted using SAS, v9.4.
A total of 404 patients met the inclusion criteria for this study. Age, body mass index, sex, and a number of levels of fusion were gathered as input data the ACS NSQIP Risk Calculator. Results of Risk Calculator were compared with observed complication rates. Descriptive statistics of the Risk Calculator risk estimates showed a significant prediction of "any complication" and "discharge to skilled nursing facility" among the cohort. Because there were no deaths or urinary tract infections, no models were fit for these outcomes.
The ACS Risk Calculator accurately predicted complications in the categories of "any complication" (P<0.0001) and "discharge to the skilled nursing facility" (P<0.001) for our cohort. We conclude that the ACS Risk Calculator was unable to accurately predict specific complications on a more granular basis for the patients of this study. Although the ACS risk calculator may be useful in the field of general surgery and in the development of new institutional strategies for risk mitigation, our findings demonstrate that it does not necessarily provide accurate information for patients undergoing cervical spinal surgery.
这是一项回顾性队列研究。
本研究的目的是评估美国外科医师学会(ACS)风险计算器准确预测颈椎手术后并发症的能力。
手术风险计算器存在于许多领域,可有助于识别并发症和再入院风险增加的患者。风险计算器可能会改善治疗结果,加强知情同意过程,并管理可改变的风险因素。美国外科医师学会国家外科质量改进计划(ACS NSQIP)风险计算器是根据超过140万患者的队列开发的,使用了2805个独特的当前手术操作术语(CPT)代码。该风险计算器使用21个患者预测因素(如年龄、美国麻醉医师协会分级、体重指数、高血压)和计划手术(CPT代码)来预测患者在手术后30天内出现12种不同结果(如死亡、任何并发症、严重并发症、再次手术)的可能性。本研究的目的是确定ACS NISQIP风险计算器能否预测颈椎融合术后30天的并发症。
对2009年1月至2015年在单一机构接受初次颈椎融合手术的患者进行回顾性病历审查,使用颈椎融合CPT代码。排除术后无30天随访的患者。计算了总体样本、前路与后路融合以及单节段与多节段融合的描述性统计数据。逻辑回归模型以实际并发症发生情况作为每个模型的因变量,以ACS估计风险作为自变量。c统计量用作每个模型一致性的度量。绘制了受试者操作特征曲线以直观描述估计风险的预测能力。可接受的一致性设定为c>0.80。所有分析均使用SAS v9.4进行。
共有404例患者符合本研究的纳入标准。收集了年龄、体重指数、性别和融合节段数作为ACS NSQIP风险计算器的输入数据。将风险计算器的结果与观察到的并发症发生率进行比较。风险计算器风险估计的描述性统计显示,该队列中对“任何并发症”和“转至熟练护理机构”有显著预测。由于没有死亡或尿路感染病例,因此未针对这些结果建立模型。
对于我们的队列,ACS风险计算器准确预测了“任何并发症”(P<0.0001)和“转至熟练护理机构”(P<0.001)类别中的并发症。我们得出结论,ACS风险计算器无法更细致地准确预测本研究患者的特定并发症。尽管ACS风险计算器可能在普通外科领域以及制定新的机构风险缓解策略方面有用,但我们的研究结果表明,它不一定能为接受颈椎手术的患者提供准确信息。