Oregon Immunization Program, Public Health Division, Oregon Health Authority, Portland, OR, USA.
Physicians Medical Center, McMinnville, OR, USA.
Public Health Rep. 2019 Nov/Dec;134(6):587-591. doi: 10.1177/0033354919879727. Epub 2019 Sep 30.
Oregon continues to face epidemics of pertussis, and infants younger than 2 months of age have the highest incidence and rates of hospitalization and complications. We describe the medical course and sequelae of an infant's severe pertussis illness through age 5½ years. The child has failed to meet developmental milestones, requires substantial medical care, and bears the burdens of chronic lung disease, stroke, epilepsy, impaired neurodevelopment, and problems with vision. The medical and social burden of pertussis among infants too young to be vaccinated underscores the importance of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccination during pregnancy.
俄勒冈州继续面临百日咳的流行,2 个月以下的婴儿发病率最高,住院率和并发症发生率也最高。我们描述了一名婴儿严重百日咳疾病的病程和后遗症,直至其 5 岁半。这名儿童未能达到发育里程碑,需要大量的医疗护理,患有慢性肺病、中风、癫痫、神经发育受损以及视力问题。对于太小而无法接种疫苗的婴儿,百日咳的医疗和社会负担突显了在怀孕期间接种破伤风类毒素、白喉类毒素减毒活疫苗和无细胞百日咳疫苗的重要性。