Latanov A V, Tereschenko L V, Ostrovsky M A
Biological Faculty, Moscow State University, Moscow, Russia.
Emanuel Institute for Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
Dokl Biol Sci. 2019 Jul;487(1):95-97. doi: 10.1134/S0012496619040069. Epub 2019 Sep 30.
The visually driven instrumental conditioning of a single monkey (Macaca mulatta) was conducted after single-dose cranial irradiation with high-energy protons. The monkey executed saccades toward the visual stimuli and then responded by manually pressing right or left lever for stimuli in right or left half-field, respectively. The percentage of correct responses with dominant right hand exceeded the percentage of such responses with left hand and temporarily decreased two months after irradiation. A month later, the percentage of correct right-hand responses returned to the level before irradiation. No significant dynamic was found for changes in percentage of correct left-hand responses. The proton irradiation effect on right-hand responses suggests possible short-term disturbances in the eye-hand coordination for right handedness while the visual perception remains unaffected.
对一只恒河猴（猕猴）进行单剂量高能质子颅脑照射后，进行了视觉驱动的工具性条件反射实验。猴子向视觉刺激执行扫视，然后分别通过手动按压右侧或左侧杠杆对右侧或左侧半视野中的刺激做出反应。用优势右手做出正确反应的百分比超过用左手做出此类反应的百分比，并且在照射后两个月暂时下降。一个月后，右手正确反应的百分比恢复到照射前的水平。未发现左手正确反应百分比变化的显著动态变化。质子照射对右手反应的影响表明，对于右利手而言，眼手协调可能存在短期干扰，而视觉感知不受影响。
