Akimov Iu A, Azhipa Ia I, Rodionov A A
Probl Endokrinol (Mosk). 1985 Jan-Feb;31(1):74-6.
A study was made of the effect of the compensatory hypertrophy of the rat kidney (on the 30th day) on the interaction of 3H-aldosterone with the receptors of the kidney cell tubules. It has been shown that the compensatory hypertrophy of the kidney is accompanied by an increased intensity of 3H-aldosterone binding with the receptors of the nephron cell cytoplasm and a decrease of the transfer of the hormonoreceptor cytoplasm and 3 receptor complex to the nucleus. These changes in the mechanism of aldosterone reception by the hypertrophic kidney can be accompanied by disturbed sensitivity of the organ to this mineralocorticoid.
