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在切片图像和表面模型上识别出苍白球丘脑束的全程。

Whole course of pallidothalamic tracts identified on the sectioned images and surface models.

机构信息

Department of Anatomy, Ajou University School of Medicine, Suwon, Republic of Korea.

Department of Anatomy, Dongguk University School of Medicine, Gyeongju, Republic of Korea.

出版信息

Clin Anat. 2020 Jan;33(1):66-76. doi: 10.1002/ca.23468. Epub 2019 Oct 14.

DOI:10.1002/ca.23468
PMID:31573101
Abstract

The anatomy of the pallidothalamic tracts, including the ansa lenticularis, lenticular fasciculus, and thalamic fasciculus (field H1 of Forel), should be elucidated by neurosurgeons and neuroscientists who study deep brain stimulation. In this study, serially sectioned images of a human cadaver head were employed to overcome the limitations of existing methods to observe the pallidothalamic tracts. Owing to the high resolution and real color of the sectioned images, 28 structures, including the pallidothalamic tracts and mammillothalamic fasciculus, were identified. The structures were segmented and made into surface models, which are helpful in improving the stereoscopic understanding. Observing the sectioned images and surface models may help in understanding the detailed anatomy of the pallidothalamic tracts. The new findings, such as the spatial relationship of the tracts, were summarized in a schematic figure. Moreover, to elucidate the anatomical structures along the course of deep brain stimulation, virtual electrodes were inserted into the surface models. The sectioned images and surface models of this study are expected to enhance the understanding of the pallidothalamic tract anatomy. A portable document format file containing the surface models and the sectioned images can be freely downloaded from the authors' homepage. Clin. Anat. 32:66-76, 2019. © 2019 Wiley Periodicals, Inc.

摘要

研究深部脑刺激的神经外科医生和神经科学家应阐明苍白球丘脑束的解剖结构,包括连合纤维束、豆状核束和丘脑束(Forel 的 H1 区)。在这项研究中,我们使用了一个人类头颅连续切片的图像来克服现有方法观察苍白球丘脑束的局限性。由于切片图像具有高分辨率和真实的颜色,可以识别出 28 个结构,包括苍白球丘脑束和乳头丘脑束。这些结构被分割并制成表面模型,有助于提高立体理解。观察切片图像和表面模型有助于了解苍白球丘脑束的详细解剖结构。新的发现,如束的空间关系,被总结在示意图中。此外,为了阐明深部脑刺激过程中的解剖结构,我们将虚拟电极插入到表面模型中。本研究的切片图像和表面模型有望增强对苍白球丘脑束解剖结构的理解。包含表面模型和切片图像的可移植文档格式文件可从作者的主页上免费下载。临床解剖学 32:66-76,2019. © 2019 Wiley Periodicals, Inc.

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