Dr. Zekai Tahir Burak Women's Health Care, Education and Research Hospital, University of Health Sciences, Ankara, Turkey.
Arch Physiol Biochem. 2022 Feb;128(1):195-199. doi: 10.1080/13813455.2019.1671457. Epub 2019 Oct 1.
We aimed to predict subsequent gestational diabetes mellitus (GDM) by fasting plasma glucose (FPG) in the first trimester.
Healthy pregnant women who were screened for GDM at 24-28 gestational weeks and had FPG levels calculated during their first antenatal visit and less than 14 gestational weeks were included in this study.
Of the 2605 women who were recruited for the study, 245 (9.4%) were diagnosed with GDM at weeks 24-28. The diagnostic accuracy for FPG predicting GDM was 66.5, 78.4, and 88.2 for the cutoff values of 87.5 mg/dl, 92 mg/dl, and 99.5 mg/dl, respectively.
FPG values which are within the normoglycaemic range constitute an independent risk factor for the development of GDM. The threshold for gestational diabetes diagnosis must be revised.
通过检测早孕期空腹血糖（FPG）预测妊娠糖尿病（GDM）。
本研究纳入了在 24-28 孕周进行 GDM 筛查且在首次产前检查时（＜14 孕周）检测到 FPG 水平的健康孕妇。
在 2605 名被招募的研究对象中，245 名（9.4%）在 24-28 孕周被诊断为 GDM。FPG 预测 GDM 的截断值为 87.5mg/dl、92mg/dl 和 99.5mg/dl 时，其诊断准确性分别为 66.5%、78.4%和 88.2%。
处于正常血糖范围内的 FPG 值是 GDM 发生的独立危险因素。妊娠期糖尿病的诊断阈值必须修订。
