• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Lessons learned from the pilot study of an orthostatic hypotension intervention in the subacute phase following spinal cord injury.脊髓损伤亚急性期体位性低血压干预试点研究的经验教训。
J Spinal Cord Med. 2019 Oct;42(sup1):176-185. doi: 10.1080/10790268.2019.1638129.
2
Electrical stimulation-evoked contractions blunt orthostatic hypotension in sub-acute spinal cord-injured individuals: two clinical case studies.电刺激诱发的收缩可减轻亚急性脊髓损伤患者的体位性低血压:两项临床病例研究
Spinal Cord. 2015 May;53(5):375-9. doi: 10.1038/sc.2014.187. Epub 2014 Nov 4.
3
Functional electrical stimulation effect on orthostatic hypotension after spinal cord injury.功能性电刺激对脊髓损伤后体位性低血压的影响
Arch Phys Med Rehabil. 2000 Feb;81(2):139-43. doi: 10.1016/s0003-9993(00)90131-x.
4
A systematic review of the management of orthostatic hypotension after spinal cord injury.脊髓损伤后体位性低血压管理的系统评价
Arch Phys Med Rehabil. 2009 May;90(5):876-85. doi: 10.1016/j.apmr.2009.01.009.
5
Treatment of Orthostatic Hypotension During Acute Inpatient Rehabilitation After Spinal Cord Injury: Usual Care vs. Anti-hypotensive Therapy.脊髓损伤后急性住院康复期间直立性低血压的治疗:常规护理与降压治疗。
Am J Hypertens. 2024 Jul 15;37(8):554-560. doi: 10.1093/ajh/hpae057.
6
Non-pharmacological management of orthostatic hypotension after spinal cord injury: a critical review of the literature.脊髓损伤后体位性低血压的非药物管理:文献综述
Spinal Cord. 2008 Oct;46(10):652-9. doi: 10.1038/sc.2008.48. Epub 2008 Jun 10.
7
Aerobic capacity, orthostatic tolerance, and exercise perceptions at discharge from inpatient spinal cord injury rehabilitation.住院脊髓损伤康复出院时的有氧能力、直立耐受力和运动感知。
Arch Phys Med Rehabil. 2013 Oct;94(10):2013-9. doi: 10.1016/j.apmr.2013.05.011. Epub 2013 Jun 5.
8
Development of a biofeedback tilt-table for investigating orthostatic syncope in patients with spinal cord injury.
Med Biol Eng Comput. 2007 Dec;45(12):1223-8. doi: 10.1007/s11517-007-0272-0. Epub 2007 Oct 27.
9
A walking disaster: a case of incomplete spinal cord injury with symptomatic orthostatic hypotension.一个行走的灾难:一例伴有症状性直立性低血压的不完全性脊髓损伤病例。
Clin Auton Res. 2015 Oct;25(5):335-7. doi: 10.1007/s10286-015-0309-7. Epub 2015 Aug 12.
10
Increased pulse wave velocity in persons with spinal cord injury: the effect of the renin-angiotensin-aldosterone system.脊髓损伤患者脉搏波速度增加:肾素-血管紧张素-醛固酮系统的影响。
Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H272-H280. doi: 10.1152/ajpheart.00544.2020. Epub 2020 Oct 23.

本文引用的文献

1
The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury.脊髓损伤神经治疗临床试验招募面临的挑战。
Spinal Cord. 2019 May;57(5):348-359. doi: 10.1038/s41393-019-0276-2. Epub 2019 Apr 8.
2
Systemic and Cerebral Hemodynamic Contribution to Cognitive Performance in Spinal Cord Injury.脊髓损伤患者认知表现的全身和脑血流动力学贡献。
J Neurotrauma. 2018 Dec 15;35(24):2957-2964. doi: 10.1089/neu.2018.5760. Epub 2018 Oct 3.
3
Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework.为随机对照试验做准备时界定可行性研究和预试验:概念框架的构建
PLoS One. 2016 Mar 15;11(3):e0150205. doi: 10.1371/journal.pone.0150205. eCollection 2016.
4
Does early exercise attenuate muscle atrophy or bone loss after spinal cord injury?早期运动能否减轻脊髓损伤后的肌肉萎缩或骨质流失?
Spinal Cord. 2016 Feb;54(2):84-92. doi: 10.1038/sc.2015.150. Epub 2015 Sep 8.
5
Reliability of the sit-up test in individuals with spinal cord injury.脊髓损伤个体仰卧起坐测试的可靠性
J Spinal Cord Med. 2015 Jul;38(4):563-6. doi: 10.1179/2045772315Y.0000000004. Epub 2015 Mar 4.
6
Clinical treatment of orthostatic hypotension after spinal cord injury with training based on electric uprise bed coupled with remote ECG and BP monitor.基于电动起立床训练联合远程心电和血压监测对脊髓损伤后体位性低血压的临床治疗
Med Sci Monit. 2014 Dec 22;20:2767-75. doi: 10.12659/MSM.891137.
7
Peak heart rates and sympathetic function in tetraplegic nonathletes and athletes.四肢瘫痪非运动员和运动员的最大心率和交感神经功能。
Med Sci Sports Exerc. 2015 Jun;47(6):1259-64. doi: 10.1249/MSS.0000000000000514.
8
Use of screening to recruitment ratios as a tool for planning and implementing spinal cord injury rehabilitation research.将筛查与招募比例用作规划和实施脊髓损伤康复研究的工具。
Spinal Cord. 2014 Oct;52(10):764-8. doi: 10.1038/sc.2014.126. Epub 2014 Aug 19.
9
Increased central arterial stiffness explains baroreflex dysfunction in spinal cord injury.中枢动脉僵硬度增加可解释脊髓损伤中的压力反射功能障碍。
J Neurotrauma. 2014 Jun 15;31(12):1122-8. doi: 10.1089/neu.2013.3280. Epub 2014 May 13.
10
Why perform a priori sample size calculation?为什么要进行先验样本量计算?
Can J Surg. 2013 Jun;56(3):207-13. doi: 10.1503/cjs.018012.

脊髓损伤亚急性期体位性低血压干预试点研究的经验教训。

Lessons learned from the pilot study of an orthostatic hypotension intervention in the subacute phase following spinal cord injury.

作者信息

Moineau Bastien, Brown Andrea, Brisbois Louise, Zivanovic Vera, Miyatani Masae, Kapadia Naaz, Hsieh Jane T C, Popovic Milos R

机构信息

KITE, Toronto Rehabilitation Institute - University Health Network , Toronto , Ontario , Canada.

Rehabilitation Sciences Institute, University of Toronto , Toronto , Ontario , Canada.

出版信息

J Spinal Cord Med. 2019 Oct;42(sup1):176-185. doi: 10.1080/10790268.2019.1638129.

DOI:10.1080/10790268.2019.1638129
PMID:31573450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6781467/
Abstract

: Following spinal cord injury (SCI) at the cervical or upper-thoracic level, orthostatic hypotension (OH) is observed in 13-100% of patients. This study aimed to test the feasibility of conducting a randomized controlled trial combining a dynamic tilt-table (Erigo) and functional electrical stimulation (FES) to mitigate OH symptoms in the subacute phase after SCI. : Pilot study. : A tertiary rehabilitation hospital. : Inpatients who had a C4-T6 SCI (AIS A-D) less than 12 weeks before recruitment, and reported symptoms of OH in their medical chart. : Screening sit-up test to determine eligibility, then 1 assessment session and 3 intervention sessions with Erigo and FES for eligible participants. : Recruitment rate, duration of assessment and interventions, resources used, blood pressure, and Calgary Presyncope Form (OH symptoms). : Amongst the 232 admissions, 148 inpatient charts were reviewed, 11 inpatients met all inclusion criteria, 7 participated in a screening sit-up test, and 2 exhibited OH. Neither of the two participants recruited in the pilot study was able to fully complete the assessment and intervention sessions due to scheduling issues (i.e. limited available time). : This pilot study evidenced the non-feasibility of the clinical trial as originally designed, due to the low recruitment rate and the lack of available time for research in participant's weekday schedule. OH in the subacute phase after SCI was less prevalent and less incapacitating than expected. Conventional management and spontaneous resolution of symptoms appeared sufficient to mitigate OH in most patients with subacute SCI.

摘要

在颈髓或胸髓上段损伤(SCI)后,13%-100%的患者会出现体位性低血压(OH)。本研究旨在测试将动态倾斜台(Erigo)和功能性电刺激(FES)相结合进行随机对照试验以减轻SCI亚急性期OH症状的可行性。:初步研究。:一家三级康复医院。:招募前不到12周发生C4-T6 SCI(美国脊髓损伤协会损伤分级A-D级)且病历中有OH症状报告的住院患者。:进行仰卧起坐筛查试验以确定入选资格,然后对符合条件的参与者进行1次评估 session和3次使用Erigo及FES的干预session。:招募率、评估和干预的持续时间、使用的资源、血压以及卡尔加里晕厥前状态量表(OH症状)。:在232例入院患者中,查阅了148份住院病历,11例住院患者符合所有纳入标准,7例参与了仰卧起坐筛查试验,2例表现出OH。由于日程安排问题(即可用时间有限),初步研究中招募的两名参与者均未能完全完成评估和干预session。:由于招募率低且参与者工作日程中缺乏研究可用时间,本初步研究证明了原设计的临床试验不可行。SCI亚急性期的OH比预期的更不常见且致残性更低。在大多数亚急性SCI患者中,常规管理和症状的自发缓解似乎足以减轻OH。