Department of Otolaryngology, Eye, Ear, Nose, and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai, China.
Department of Otolaryngology-Head and Neck Surgery, Stanford University Medical Center, Stanford, CA.
Int Forum Allergy Rhinol. 2019 Nov;9(11):1263-1272. doi: 10.1002/alr.22437. Epub 2019 Oct 1.
Surgery remains the mainstay of treatment for lesions in the parapharyngeal space. However, gaining access to the parapharyngeal space is often challenging. In this study we aim to describe a minimally invasive technique of approaching the upper parapharyngeal space through an endoscopic transnasal retropterygoid approach, based on anatomic studies and surgeries.
Six fresh human cadaver heads were prepared for anatomic study at the Surgical Neuroanatomy Laboratory of the Center for Cranial Base Surgery within the Department of Neurological Surgery at the University of Pittsburgh School of Medicine. Three clinical cases seen in the Department of Otolaryngology, Eye, Ear, Nose, and Throat Hospital, Shanghai Medical College of Fudan University, were used to illustrate the technique and feasibility of this approach and to assess its indications, advantages, and drawbacks.
The medial pterygoid plate is the primary landmark of the endoscopic transnasal retropterygoid approach to the upper parapharyngeal space. Access to the upper parapharyngeal space could be obtained by removing the mucosa on the medial pterygoid plate and the mucosa below the pharyngeal orifice of the Eustachian tube. The 3 patients in our study tolerated the procedure well and had no serious complications after surgery.
The anatomic data and clinical cases in this study confirm that an endoscopic transnasal retropterygoid approach is a feasible and effective surgical treatment for selected tumors in the upper parapharyngeal space.
手术仍然是治疗咽旁间隙病变的主要方法。然而,进入咽旁间隙往往具有挑战性。在这项研究中,我们旨在描述一种通过经鼻内镜经蝶入路进入上咽旁间隙的微创技术,该技术基于解剖学研究和手术。
在匹兹堡大学医学院神经外科颅底外科中心的外科神经解剖实验室,对 6 个新鲜的人体头颅进行解剖学研究准备。我们使用上海医科大学眼耳鼻喉科医院耳鼻喉科的 3 个临床病例来说明该技术的方法和可行性,并评估其适应证、优点和缺点。
翼内板是经鼻内镜经蝶入路上咽旁间隙的主要标志。通过去除翼内板的粘膜和咽鼓管咽口下方的粘膜,可以进入上咽旁间隙。我们研究中的 3 名患者对该手术耐受良好,术后无严重并发症。
本研究的解剖学数据和临床病例证实,经鼻内镜经蝶入路是治疗上咽旁间隙选定肿瘤的一种可行有效的手术治疗方法。