Zhou Yong, Lin Li, Chen Zhengyun, Wang Yuan, Chen Chaolu, Li Enchun, Wu Ruijin
Women's Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, People's Republic of China.
Medicine (Baltimore). 2019 Sep;98(39):e16965. doi: 10.1097/MD.0000000000016965.
This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy.A total of 107 women who wished to conceive after surgery for recurrent endometriosis from January 2007 to December 2016 were included. The EFI score was calculated postoperatively. The receiver operator characteristic (ROC) curve was plotted to determine the most promising contributor to predicting pregnancy, and Kaplan-Meier (K-M) analysis was used to estimate the cumulative pregnancy rate (CPR).A total of 61 pregnancies were registered in 58 women and the remaining 49 patients failed to become pregnant. The EFI score was strongly associated with the postoperative fertility prognosis. The CPRs during the first 2 and 3 years postoperatively were 51.86% and 66.38%, respectively, and increased to 71.98% within the first 5 years postoperatively in patients with EFI scores ≥5. However, the CPR was 26.00% during the first 2 years after surgery in individuals with EFI scores <5, and there was no increase in the CRP thereafter.Women suffering from recurrent endometriosis still experienced a probability of natural pregnancy, especially patients with EFI scores ≥5. The EFI score had good predictive power for postoperative pregnancy in these patients.
本研究呈现了复发性子宫内膜异位症女性的术后妊娠率，并评估了子宫内膜异位症生育指数（EFI）对妊娠的预测价值。纳入了2007年1月至2016年12月期间因复发性子宫内膜异位症手术后希望怀孕的107名女性。术后计算EFI评分。绘制受试者工作特征（ROC）曲线以确定预测妊娠最有前景的因素，并采用Kaplan-Meier（K-M）分析来估计累积妊娠率（CPR）。58名女性共登记了61次妊娠，其余49例患者未怀孕。EFI评分与术后生育预后密切相关。EFI评分≥5的患者术后第1年和第3年的CPR分别为51.86%和66.38%，术后前5年内增至71.98%。然而，EFI评分<5的个体术后第1年的CPR为26.00%，此后CRP无增加。患有复发性子宫内膜异位症的女性仍有自然妊娠的可能性，尤其是EFI评分≥5的患者。EFI评分对这些患者的术后妊娠具有良好的预测能力。
