超声血管造影联合细针穿刺对甲状腺结节诊断的影响
Impact of ultrasound angiography combined with fine needle aspiration for the diagnosis of thyroid nodules.
作者信息
Wang Jing, Bai Xiao-Gang, Liu Zhe
机构信息
Department of Endocrine and Metabolism.
Department of Cardiology, Yan'an University Affiliated Hospital, Yan'an, China.
出版信息
Medicine (Baltimore). 2019 Sep;98(39):e17286. doi: 10.1097/MD.0000000000017286.
BACKGROUND
This study aims to systematically investigate the impact of ultrasound angiography (UA) combined with fine needle aspiration (FNA) for the diagnosis of thyroid nodules (TNs).
METHODS
The following electronic databases will be searched: MEDLINE, EMBASE, Cochrane Library, PsycINFO, Web of Science, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. We will search them from their inceptions to the present without language limitations. We will consider all case-controlled studies on investigating the impact of diagnosis UA combined FNA for TNs. We will apply Quality Assessment of Diagnostic Accuracy Studies tool to assess methodological quality for all eligible studies.
RESULTS
In this study, outcomes consist of sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio. All these outcomes will be analyzed to evaluate the diagnostic accuracy of UA combined with FNA for TNs.
CONCLUSION
This study will provide evidence of the diagnostic accuracy of UA combined with FNA for TNs.
SYSTEMATIC REVIEW REGISTRATION
PROSPERO CRD42019138884.
背景
本研究旨在系统调查超声血管造影（UA）联合细针穿刺抽吸（FNA）对甲状腺结节（TNs）诊断的影响。
方法
将检索以下电子数据库：MEDLINE、EMBASE、Cochrane图书馆、PsycINFO、科学网、护理及相关健康文献累积索引、补充与替代医学数据库、中国生物医学文献数据库和中国知网。我们将从各数据库建库起至目前进行检索，无语言限制。我们将纳入所有关于研究UA联合FNA对TNs诊断影响的病例对照研究。我们将应用诊断准确性研究质量评估工具来评估所有符合条件研究的方法学质量。
结果
在本研究中，结局指标包括敏感性、特异性、阳性似然比、阴性似然比和诊断比值比。将对所有这些结局指标进行分析，以评估UA联合FNA对TNs的诊断准确性。
结论
本研究将为UA联合FNA对TNs的诊断准确性提供证据。
系统评价注册
PROSPERO CRD42019138884
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