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2型糖尿病退伍军人血脂管理中的种族地理差异:一项10年回顾性队列研究

Racial-Geographic Disparity in Lipid Management in Veterans with Type 2 Diabetes: A 10-Year Retrospective Cohort Study.

作者信息

Brown Elizabeth A, Ward Ralph C, Weeda Erin, Taber David J, Axon Robert Neal, Gebregziabher Mulugeta

机构信息

Department of Health Professions, College of Health Professions, Medical University of South Carolina, Charleston, South Carolina.

Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, South Carolina.

出版信息

Health Equity. 2019 Sep 23;3(1):472-479. doi: 10.1089/heq.2019.0071. eCollection 2019.

Abstract

The prevalence of diabetes in U.S. veterans (20.5%) is nearly three times that of the general population. Minority veterans have higher rates of diabetes compared with their counterparts and urban/rural residence is also associated with uncontrolled cholesterol. However, the interplay between urban/rural residence and race/ethnicity on cholesterol control is unclear. Veterans Health Administration Corporate Data Warehouse and Centers for Medicare and Medicaid data were used to create unique dataset and perform longitudinal study of veterans with type 2 diabetes from 2006 to 2016. Logistic regression was used to model the association between low-density lipoprotein (LDL) control and the primary exposures (race/ethnicity and location of residence) after adjusting for all measured covariates, including the interaction between location of residence and race/ethnicity. There was a significant interaction between race/ethnicity and rural residence. Rural non-Hispanic Black (NHB) veterans had higher odds for LDL >100 mg/dL (odds ratio [OR]=1.70, 95% confidence interval [CI] 1.50-1.60) and for LDL >70 mg/dL (OR=1.59, 95% CI 1.53-1.64) compared with urban non-Hispanic White (NHW) veterans. Similarly, compared with urban NHW, urban NHB veterans had higher odds of LDL >100 mg/dL (OR=1.45, 95% CI 1.43-1.47) and LDL >70 mg/dL (OR=1.36, 95% CI 1.34-1.38). This study highlights health disparities for veterans with type 2 diabetes. Future research is needed to evaluate interventions for mitigating these disparities in cholesterol management among veterans with diabetes.

摘要

美国退伍军人中糖尿病的患病率(20.5%)几乎是普通人群的三倍。少数族裔退伍军人的糖尿病发病率高于其相应群体,而且城乡居住情况也与胆固醇控制不佳有关。然而,城乡居住情况与种族/族裔在胆固醇控制方面的相互作用尚不清楚。利用退伍军人健康管理局企业数据仓库以及医疗保险和医疗补助服务中心的数据创建了独特的数据集,并对2006年至2016年的2型糖尿病退伍军人进行了纵向研究。在对所有测量的协变量进行调整后,包括居住地点与种族/族裔之间的相互作用,采用逻辑回归对低密度脂蛋白(LDL)控制与主要暴露因素(种族/族裔和居住地点)之间的关联进行建模。种族/族裔与农村居住情况之间存在显著的相互作用。与城市非西班牙裔白人(NHW)退伍军人相比,农村非西班牙裔黑人(NHB)退伍军人LDL>100mg/dL的几率更高(优势比[OR]=1.70,95%置信区间[CI]1.50 - 1.60),LDL>70mg/dL的几率也更高(OR=1.59,95%CI 1.53 - 1.64)。同样,与城市NHW退伍军人相比,城市NHB退伍军人LDL>100mg/dL(OR=1.45,95%CI 1.43 - 1.47)和LDL>70mg/dL(OR=1.36,95%CI 1.34 - 1.38)的几率更高。这项研究凸显了2型糖尿病退伍军人的健康差异。未来需要开展研究,以评估减轻糖尿病退伍军人胆固醇管理方面这些差异的干预措施。

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