Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Helmintos Parasitos de Vertebrados, Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Mosquitos Transmissores de Hematozoários, Rio de Janeiro, RJ, Brasil.
Mem Inst Oswaldo Cruz. 2019 Sep 26;114:e190149. doi: 10.1590/0074-02760190149. eCollection 2019.
Human polycystic echinococcosis is a parasitic infection caused by the larval stage of Echinococcus vogeli, which occurs in rural areas of Central and South America. Until now, little information on the genetic variability of E. vogeli is available. Here, 32 samples from human-excised E. vogeli cysts had a 396-bp sequence of the mitochondrial cytochrome oxidase I (COI) gene sequenced and compared to another 17 COI sequences representing nine Echinococcus species. A Bayesian COI tree revealed that all E. vogeli sequences formed a monophyletic and well-supported clade with an E. vogeli reference sequence. The occurrence of geographically restricted E. vogeli COI haplotypes suggests retention of ancestral polymorphisms with little migration in Acre, Brazil.
人类多房棘球蚴病是一种寄生虫感染，由细粒棘球绦虫的幼虫期引起，主要发生在中美洲和南美洲的农村地区。到目前为止，关于细粒棘球绦虫的遗传变异性的信息很少。在这里，对 32 个人工切除的细粒棘球蚴囊的线粒体细胞色素氧化酶 I（COI）基因的 396bp 序列进行了测序，并与代表 9 种细粒棘球绦虫的另外 17 个 COI 序列进行了比较。贝叶斯 COI 树表明，所有细粒棘球绦虫序列都形成了一个单系的、支持良好的分支，与细粒棘球绦虫的参考序列一致。在巴西阿克里州，COI 单倍型的地理分布有限，这表明在那里，祖先的多态性得以保留，迁移很少。
