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[阿尔泰边疆区和莫斯科州野生小鼠对莫兹多克血清型钩端螺旋体和波摩那群钩端螺旋体易感性的差异]

[Differences in the susceptibility of field mice from the Altai Territory and Moscow Province to Leptospira of serovar mozdok and serogroup Pomona].

作者信息

Chernukha Iu G, Evdokimova O A, Anan'ina Iu V, Chekhovich A V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Feb(2):45-9.

PMID:3158138
Abstract

Adult striped field mice (Apodemus agrarius) caught in the Altai region proved to be insusceptible to experimental infection when inoculated with Leptospira of serovar mozdok, serogroup Pomona. In pregnant females, though infected with this organism, no leptospiruria was observed. At the same time nonpubescent animals became Leptospira carriers, females becoming carriers 4.5 times more frequently than males. The formation of antibodies to Leptospira in the test rodents was poorly pronounced and did not depend on their sex, age, physiological state and the presence of renal leptospirosis. But all adult striped field mice belonging to the population of the Moscow region became Leptospira carriers in such experiments.

摘要

在阿尔泰山地区捕获的成年条纹田鼠(黑线姬鼠)接种波摩那群莫兹多克血清型钩端螺旋体后,经实验感染证明不易感。怀孕雌性虽感染该病原体,但未观察到钩端螺旋体尿。同时,未成年动物成为钩端螺旋体携带者,雌性成为携带者的频率比雄性高4.5倍。受试啮齿动物中针对钩端螺旋体的抗体形成不明显,且不取决于它们的性别、年龄、生理状态及肾钩端螺旋体病的存在情况。但在这类实验中,所有来自莫斯科地区种群的成年条纹田鼠都成为了钩端螺旋体携带者。

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