家族健康史：精准医学中的首次基因检测。

Family Health History: The First Genetic Test in Precision Medicine.

机构信息

Division of Medical Genetics, Department of Medicine, University of Washington, University of Washington Medical Center, Box 357720, 1959 Northeast Pacific Street, Seattle, WA 98195-7720, USA.

出版信息

Med Clin North Am. 2019 Nov;103(6):957-966. doi: 10.1016/j.mcna.2019.06.002. Epub 2019 Aug 24.

DOI:10.1016/j.mcna.2019.06.002

PMID:31582006

Abstract

The collection of family history has always been a tool for genetic evaluation, but it remains an essential tool even in the age of genomic medicine. Patients may have a risk for a disease based on family history regardless of the results of genetic and genomic tests. How this information is collected is less important than that relevant information is collected in the first place. There are many tools for collecting medical and family history information both by hand and electronically. Genetic and genomic testing should always be interpreted in the context of the personal and family history.

摘要

家族史的收集一直是遗传评估的工具，但即使在基因组医学时代，它仍然是一个必不可少的工具。患者可能基于家族史而存在患病风险，而不论遗传和基因组测试的结果如何。信息的收集方式并不重要，重要的是首先收集到相关信息。有许多工具可用于通过手动和电子方式收集医疗和家族史信息。遗传和基因组测试应始终根据个人和家族史进行解释。