Pathology, University of Health Sciences Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.
Family Medicine, University of Health Sciences Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.
Obes Surg. 2020 Feb;30(2):478-482. doi: 10.1007/s11695-019-04185-9.
The aim of this study was to investigate the correlation between histopathologic findings detected in laparoscopic sleeve gastrectomy (LSG) specimens and excess weight loss percentages (%EWL) and excess BMI decrease percentages (%EBL).
Patients who underwent LSG in the hospital's Gastroenterological Surgery Department between the years 2013 and 2018 and who completed 1 year of follow-up were involved in the study. Patients whose 6th month and 12th month BMI were unknown were excluded from the study. Clinical and pathologic data of the cases were obtained from the automation system of the hospital.
As a result of comparison among diagnosis groups, it was detected in the histopathologic analysis that the 12th month mean %EWL measurement was higher in the inactive stomach diagnosis group. In the comparisons among intestinal metaplasia (IM) groups, it was seen that 6th month %EWL and %EBL and 12th month %EWL and %EBL measurements were higher in the group without IM. Age, baseline BMI and active gastritis incidence in histopathologic analysis have a negative effect on weight loss.
A correlation of histopathologic changes in morbid obese patients with weight loss after bariatric surgery was asserted in this study. Operating on younger patients with lower BMI and inactive gastritis with the LSG method could contribute to achieving more successful results. Prospective research studies are necessary within this context.
本研究旨在探讨腹腔镜袖状胃切除术（LSG）标本中组织病理学发现与超重减轻百分比（%EWL）和超重 BMI 降低百分比（%EBL）之间的相关性。
本研究纳入了 2013 年至 2018 年在医院胃肠外科接受 LSG 并完成 1 年随访的患者。排除了 6 个月和 12 个月 BMI 未知的患者。从医院自动化系统中获取了病例的临床和病理数据。
在诊断组之间的比较中，在组织病理学分析中发现，非活动胃诊断组的 12 个月平均%EWL 测量值较高。在肠化生（IM）组之间的比较中，发现无 IM 组的 6 个月%EWL 和%EBL 以及 12 个月%EWL 和%EBL 测量值较高。组织病理学分析中的年龄、基线 BMI 和活动性胃炎的发生率对减重有负面影响。
本研究证实了病态肥胖患者的组织病理学变化与减肥手术减肥之间的相关性。采用 LSG 方法对年轻、BMI 较低和无活动性胃炎的患者进行手术可能有助于取得更成功的结果。在此背景下，需要进行前瞻性研究。
