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高海拔地区人群原发性高血压的患病率及临床特点

Prevalence and clinical peculiarities of essential hypertension in a population living at high altitude.

作者信息

Mirrakhimov M M, Rafibekova Zh S, Dzhumagulova A S, Meimanaliev T S, Murataliev T M, Shatemirova K K

出版信息

Cor Vasa. 1985;27(1):23-8.

PMID:3158478
Abstract

Screening examinations were performed in ethnically related populations of men aged 30-59 years, living in high mountain regions of Tien-Shan and Pamir (2800-3600 m above sea level) and in the lowlands (800-900 m). The incidence of borderline hypertension (BH) and essential hypertension (EH) was statistically significantly higher among the inhabitants of lowland regions: EH was recorded among them in 15.4%, vs. 4.2% among men living at high altitude; BH was present among the male lowland population (LL) in 10.6% vs. 6.0% among highlanders (HL). The main characteristic clinico-functional feature of EH in HL was its frequent association with high-altitude pulmonary hypertension and right ventricular hypertrophy. Aldosterone excretion was in HL with EH substantially lower, and sodium excretion higher, than in a comparable group of lowland inhabitants.

摘要

对居住在天山和帕米尔高原高山区(海拔2800 - 3600米)以及低地(海拔800 - 900米)的30 - 59岁男性相关种族人群进行了筛查检查。低地地区居民中临界高血压(BH)和原发性高血压(EH)的发病率在统计学上显著更高:低地地区居民中记录到EH的比例为15.4%,而生活在高海拔地区的男性中这一比例为4.2%;低地男性人群(LL)中存在BH的比例为10.6%,而高地人群(HL)中这一比例为6.0%。高海拔地区EH的主要临床功能特征是其常与高原肺动脉高压和右心室肥厚相关。高海拔地区患EH者的醛固酮排泄量明显低于可比的低地居民组,而钠排泄量则更高。

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