Division of Neurosurgery, Children's National Health System, Washington, District of Columbia.
Division of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, Maryland.
Neurosurgery. 2020 Jul 1;87(1):80-85. doi: 10.1093/neuros/nyz387.
Although ventriculoperitoneal shunts (VPS) remain the first-line option in most instances of pediatric hydrocephalus, the long-term efficacy of ventriculoatrial shunts (VAS) remains unknown.
To characterize the long-term outcomes and adverse occurrences associated with both VPS and VAS at our institution.
The authors retrospectively analyzed all cerebrospinal fluid (CSF) shunting procedures performed over a 13-yr period at a single institution. A total of 544 pediatric shunt patients were followed for at least 90 d (VPS: 5.9 yr; VAS: 5.3 yr).
A total of 54% of VPS and 60% of VAS required at least 1 revision. VPS demonstrated superior survival overall; however, if electively scheduled VAS lengthening procedures are not considered true "failures," no statistical difference is noted in overall survival (P = .08). VPS demonstrated significantly greater survival in patients less than 7 yr of age (P = .001), but showed no difference in older children (P = .4). VAS had a significantly lower rate of infection (P < .05) and proximal failure (P < .001).
VAS can be a useful alternative to VPS when the abdomen is unsuitable, particularly in older children. Although VPS demonstrates superior overall survival, it should be understood that elective VAS lengthening procedures are often necessary, especially in younger patients. If elective lengthening procedures are not considered true failures, then the devices show similar survival.
尽管脑室-腹腔分流术(VPS)在大多数小儿脑积水的情况下仍然是首选治疗方法,但脑室-心房分流术(VAS)的长期疗效仍不清楚。
描述本机构 VPS 和 VAS 的长期结果和不良事件。
作者回顾性分析了一家机构在 13 年内进行的所有脑脊液(CSF)分流手术。共有 544 名小儿分流患者至少随访 90 天(VPS:5.9 年;VAS:5.3 年)。
VPS 中有 54%和 VAS 中有 60%需要至少一次修订。VPS 的总体生存率更高;然而,如果不将选择性计划的 VAS 延长手术视为真正的“失败”,则总体生存率没有统计学差异(P=0.08)。VPS 在年龄小于 7 岁的患者中生存率显著更高(P=0.001),但在年龄较大的儿童中没有差异(P=0.4)。VAS 的感染率(P<0.05)和近端故障(P<0.001)显著较低。
当腹部不适时,VAS 可以作为 VPS 的有效替代方法,特别是在年龄较大的儿童中。尽管 VPS 的总体生存率更高,但应理解,特别是在年轻患者中,通常需要进行选择性的 VAS 延长手术。如果不将选择性延长手术视为真正的失败,则这些装置的生存率相似。