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去氨基二碳-催产素和催产素对犬子宫、胃和小肠肌电及机械活动的影响。

Effect of deamino-dicarba-oxytocin and oxytocin on myoelectrical and mechanical activity of uterus, stomach and small intestine in dog.

作者信息

Milenov K, Barth T, Jost K, Kasakov L

出版信息

Endocrinol Exp. 1979 Sep;13(3):177-83.

PMID:315869
Abstract

In conscious dog deamino-dicarba-oxytocin strongly stimulated a spike activity in the uterus which was more prolonged than that after oxytocin. Both oxytocin and deamino-dicarba-oxytocin inhibited the tone and peristaltic contractions of stomach and small intestines in starving dogs, eliminated the spike discharges, reduced the basic electrical rhythm frequency of the stomach and accelerated the propagation velocity of the slow waves in the small intestine. Only oxytocin, but not its deamino-analogue, reduced the pulse frequency and inhibited the spontaneous contractions of muscle strips isolated from the guinea pig stomach and portal vein.

摘要

在清醒犬中,脱氨基二碳-催产素强烈刺激子宫中的峰电位活动,其持续时间比催产素后的更长。催产素和脱氨基二碳-催产素均抑制饥饿犬胃和小肠的张力及蠕动收缩,消除峰电位发放,降低胃的基本电节律频率,并加快小肠慢波的传播速度。只有催产素,而非其脱氨基类似物,降低豚鼠胃和门静脉分离的肌条的脉冲频率并抑制其自发收缩。

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Effect of deamino-dicarba-oxytocin and oxytocin on myoelectrical and mechanical activity of uterus, stomach and small intestine in dog.去氨基二碳-催产素和催产素对犬子宫、胃和小肠肌电及机械活动的影响。
Endocrinol Exp. 1979 Sep;13(3):177-83.
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Effect of oxytocin on contraction of rabbit proximal colon in vitro.催产素对兔离体近端结肠收缩的影响。
World J Gastroenterol. 2003 Jan;9(1):165-8. doi: 10.3748/wjg.v9.i1.165.