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膀胱内前列腺突入的厚度与高度比预测前列腺动脉栓塞治疗良性前列腺增生的临床疗效和并发症。

Thickness-to-Height Ratio of Intravesical Prostatic Protrusion Predicts the Clinical Outcome and Morbidity of Prostatic Artery Embolization for Benign Prostatic Hyperplasia.

机构信息

Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Room 2A061, 2/F, Main Clinical Block and Trauma Centre, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong SAR; Vascular and Interventional Radiology Foundation Clinical Science Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Room 2A061, 2/F, Main Clinical Block and Trauma Centre, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong SAR.

Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Room 2A061, 2/F, Main Clinical Block and Trauma Centre, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong SAR; Vascular and Interventional Radiology Foundation Clinical Science Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Room 2A061, 2/F, Main Clinical Block and Trauma Centre, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong SAR.

出版信息

J Vasc Interv Radiol. 2019 Nov;30(11):1807-1816. doi: 10.1016/j.jvir.2019.07.035. Epub 2019 Oct 3.

Abstract

PURPOSE

To evaluate the presence of intravesical prostatic protrusion (IPP) and its thickness-to-height (T/H) ratio as a predictor for the clinical outcome and morbidity of prostatic artery embolization (PAE) for benign prostatic hyperplasia.

MATERIALS AND METHODS

This was a prospective, single-center, institutional review board-approved study from June 2015 to December 2018 of 82 consecutive patients (age, 53-79 years; median, 66 years) with International Prostate Symptom Score (IPSS) ≥15 and quality-of-life (QOL) score ≥3. The presence of IPP and its T/H ratio were assessed on baseline magnetic resonance imaging for their correlation with the clinical outcomes of suboptimal IPSS (IPSS ≥10) and suboptimal QOL (QOL ≥3) up to 12 months after PAE and the occurrence of post-procedure complications (≤30 days), which caused a certain degree of urinary outflow obstruction. The chi-squared test was used for analysis.

RESULTS

IPP was present in 57 of 82 patients (69.5%). The presence of IPP correlated with the occurrence of post-procedure complications (P = .009) but not with suboptimal IPSS at 12 months (P = .758). IPP with a T/H ratio ≤1.3 correlated with suboptimal IPSS at 12 months (P = .025) and suboptimal QOL at 6 months (P = .025) and 12 months (P = .008), as well as with the occurrence of post-procedure complications (P = .009).

CONCLUSIONS

IPP with a T/H ratio ≤1.3 predicted the occurrence of post-procedure complications with urinary obstruction. A T/H ratio ≤1.3 but not the presence of IPP alone predicted the clinical outcome up to 12 months after PAE.

摘要

目的

评估膀胱内前列腺突入(IPP)及其厚度与高度比(T/H)作为前列腺动脉栓塞(PAE)治疗良性前列腺增生的临床疗效和发病率的预测因子。

材料与方法

这是一项前瞻性、单中心、机构审查委员会批准的研究,于 2015 年 6 月至 2018 年 12 月期间连续入组 82 例患者(年龄 53-79 岁,中位数 66 岁),这些患者的国际前列腺症状评分(IPSS)≥15 分,生活质量评分(QOL)≥3 分。在基线磁共振成像上评估 IPP 的存在及其 T/H 比值,以评估其与 PAE 后 12 个月内亚优 IPSS(IPSS≥10)和亚优 QOL(QOL≥3)的临床结果以及术后并发症(≤30 天)的相关性,这些并发症导致一定程度的尿流梗阻。采用卡方检验进行分析。

结果

82 例患者中有 57 例(69.5%)存在 IPP。IPP 的存在与术后并发症的发生相关(P=0.009),但与 12 个月时的亚优 IPSS无关(P=0.758)。IPP 的 T/H 比值≤1.3 与 12 个月时的亚优 IPSS(P=0.025)、6 个月和 12 个月时的亚优 QOL(P=0.025 和 P=0.008)以及术后并发症的发生(P=0.009)相关。

结论

IPP 的 T/H 比值≤1.3 预测了伴有尿路梗阻的术后并发症的发生。T/H 比值≤1.3 而不是单纯的 IPP 存在预测了 PAE 后 12 个月的临床结果。

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